Previous studies have demonstrated that there are various levels of inflammatory responses in patients who suffer from asthma, and
allergic airway inflammation with increasing EOS is the main pathological feature of asthma (20,21).
Not exact matches
Specifically, the researchers found that a peptide, called STAT6 - IP, when delivered to the lungs of neonatal mice at the time of first RSV exposure reduces the development of
allergic - type lung
inflammation and
airway hyperresponsiveness («twitchy»
airways) in mice when they are «re-challenged»
with RSV as young adults.
Tobias Polte and his team from the Department of Environmental Immunology at the Helmholtz Centre for Environmental Research (UFZ) collaborated
with Jan Simon and his colleagues from the Clinic for Dermatology, Venereology and Allergology at the University of Leipzig and have recently been successful in discovering a molecule that plays a significant role in the development of
allergic airway inflammation — as demonstrated in their recent publication in Nature Communications.
Enhanced Expression of Myristoylated Alanine — Rich C Kinase Substrate (MARCKS) in
Airway Epithelium of an Animal Model of
Allergic Airway Inflammation and Human Patients
with COPD
The slides were stained
with Diff - Quick (Polysciences, Warrington, PA), and differential cell counts were performed to assess
allergic airway inflammation.
An
inflammation of the nasal
airways,
allergic rhinitis is linked
with a sensitized immune system that overreacts to what should be a benign stimulant.
In one study, researchers at the University of Connecticut found that bromelain reduced
airway inflammation in animals
with allergic airway disease.