Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in
allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis,
allergic rhinitis, immunopharmacological modulation of
allergic diseases
by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the
allergic effector unit, mast cell derived tumors: new antibody based treatment, the
allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels
In the same Finnish cohort that found doses of vitamin D in excess of 2,000 IU per day during infancy to powerfully protect against type 1 diabetes (see sidebar «Vitamin D and Type 1 Diabetes below), regular supplementation with vitamin D was associated with a 33 percent increased risk of atopy and
allergic rhinitis compared to irregular or no supplementation; among those who supplemented regularly, the data suggested that supplementation with 2000 IU or more per day may increase the risk of asthma
by as much as four times compared to regular supplementation with lower doses, although the study lacked the statistical power to determine whether or not this apparent effect was due to chance.34
Koinis - Mitchell is the principal investigator of a study funded
by the National Institutes of Health that examines the co-occurrence of sleep quality and academic performance in urban children who have asthma and
allergic rhinitis, as well as healthy children.