Sentences with phrase «allocation concealment did»
Information on randomisation and allocation concealment did not appear in any study report.
http://cochranelibrary-wiley.com/ Not exact matches
Each week, the study co-ordinator used SPSS software (SPSSInc, Chicago, IL) to randomly assign 50 % of newly recruited participants to the intervention group, thus preserving allocation concealment (not sure how they did this using SPSS).
«But human trials of sitagliptin have been limited to date because they have lacked important tools like a placebo arm and allocation concealment (in which researchers do not know what the next treatment allocation will be, further preventing selection bias in testing),» said Loomba.
To ensure baseline allocation concealment, the project coordinator does not randomise until the participant is recruited into the trial; that is, after the participant provides informed consent, all the inclusion and exclusion criteria are addressed, the eligibility of the participant is confirmed and all baseline measurements are completed.
A number of methodological studies provide empirical evidence to support these precautions.152 153 Trials in which the allocation sequence had been inadequately or unclearly concealed yielded larger estimates of treatment effects than did trials in which authors reported adequate allocation concealment.