Sentences with phrase «allogeneic immune surveillance»
One possible role of FMc in healthy women might be the provision of allogeneic immune surveillance for (pre --RRB- malignant cells.
http://journals.plos.org/ Not exact matches
Interestingly tumor cells, whilst not allogeneic, are in many cases both «altered - self» and immunogenic but often actively modulate immune responsiveness to evade immune surveillance 76.
Allogeneic cells, particularly mismatched or haploidentical cells, in the context of hematopoietic transplantation have been found to provide potent immune surveillance for both hematologic and solid tumor malignancies in a process referred to as graft - versus - tumor [13]--[15].
These allogeneic cells have the potential to participate in immune surveillance for breast or other cancers as observed in clinical hematopoietic stem cell transplantation.
By integrating the aforementioned observations of FMc in autoimmunity and transplantation immunobiology, we reasoned that allogeneic FMc might provide immune surveillance for breast cancer in parous women.