Sentences with phrase «allogeneic recipients»
Furthermore, 38 percent of allogeneic recipients who participated at the three - year mark had not yet returned to work, and impairment was associated with a tenfold increased odds of not returning to work at three years post-transplant.
https://www.sciencedaily.com/ Not exact matches
In contrast, injections of the cells into immunologically unmatched recipients (called an allogeneic transplantation) caused the body to mount a stronger immune response.
«From this data, it's clear that we have to make strides in supporting allogeneic BMT recipients in their recovery to ensure that we are educating patients and their families on signs of cognitive impairment.
These reports suggest that transplantation of MSC could be beneficial in patients with various disorders requiring tissue regeneration, and provide evidence supporting the tolerance of allogeneic MSC by recipients.
Hematopoietic stem cells express the markers CD34 and CD133 and can repopulate a myeloablated recipient after allogeneic or autologous transplantation.
To evaluate the impact of VPA treatment on the preservation of GVL activity, we challenged BALB / c recipients with host - type GFP + acute myeloid leukemia cells (H - 2d) to mimic residual leukemia in patients receiving allogeneic BMT.
VPA was administered i.p. to allogeneic BMT recipients from day 0, with vehicle treatment as control.
The infiltration of Th1 and Th17 cells into GVHD target organs (liver and lung), as well as the serum level of related cytokines, also were increased in allogeneic BMT recipients.
In contrast, we found that VPA caused a slight decrease in the number of CD4 + Tregs in allogeneic BMT recipients.
If these results are confirmed and one or more of these FLT3 - targeted drugs become approved by the FDA, testing for the FLT3 biomarker may eliminate the need for thousands of patients to undergo stem cell transplantation (each allogeneic transplant costs hundreds of thousands of dollars and place recipients at grave risk of infection and other complications such as Graft vs. Host disease).