Sentences with phrase «allogenic es»
For these reasons, conditioning recipients of allogenic ES cell - derived HPCs could potentially be safer and less rigorous than conditioning recipients of bone marrow cells.
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Although a number of groups have already looked at the engraftment of ES - derived HPCs in Rag2 − / − γc − / − mice, there are no reports on HPC engraftment in either syngeneic or allogenic immunocompetent mice.
Our data show, for the first time, the efficacy of ES - derived CD45 + HPCs to engraft in allogenic recipients without the use of immunosuppressive agents, there by protecting cardiac allografts from rejection.
In addition to the high degree of pluripotency, ES cells can generate newly - differentiated cells that appear to have low immunogenicity, an ideal property for allogenic transplantation.