Sentences with phrase «allografts underwent»

Experiments were performed to confirm that a significant number of corneal allografts underwent rejection in the absence of CD4 + T cells.

The results indicated that 54 % (38/70) of the BALB / c corneal allografts underwent rejection in the CD4 KO hosts, while 100 % of the grafts were rejected in wild - type C57BL / 6 mice (Figure 1).

BALB / c corneal allografts underwent rejection in 46 % (6/13; MST = 46 days) of the recipients of CD8 − T lymphocytes and in 95 % (19/20; MST = 15 days) of the recipients of CD8 + T lymphocytes (Figure 2B).

However, closer scrutiny of these studies raises questions about the role of CD4 + T cells as the sole mediators of corneal graft rejection, as corneal allografts undergo immune rejection in 33 % of the mice and 64 % of the rats treated with anti-CD4 monoclonal antibody (12, 13) and in 45 % of the CD4 KO mice (14).

Several studies suggest that a significant number of corneal allografts undergo rejection in the absence of CD4 + T cells.

Not exact matches

This preparation provides access to the patient's own stem cells, which may undergo osteogenic differentiation in response to delivery of the allograft BMDMSC.