Sentences with phrase «allow cell therapies»

He is also working on new receptor types that could allow cell therapies to more effectively penetrate disease sites and reside there for the duration of the treatment.

The encapsulation device is designed to protect the cells from being destroyed by the immune system and allows the cell therapy to be removed and replaced as necessary.

Not exact matches

Human Longevity has already received $ 70 million in private backing and aims to use both genomics and stem cell therapies to allow us to live longer, healthier lives.

One of the molecular mysteries hindering development of regenerative therapy for muscles is uncovering the precise genetic and molecular processes that cause skeletal muscle stem cells (called myoblasts) to fuse and form the striated muscle fibers that allow movement.

«It may sound like an appealing idea to allow seriously ill patients accelerated access to experimental therapies,» Sally Temple, the president of the International Society for Stem Cell Research, wrote to Texas lawmakers this month.

Being able to acquire new technologies, as well as becoming more innovative internally by venturing into new research areas, such as stem cell and gene therapy research, have allowed Genzyme to maintain its edge.

The concerns of the scientific community have been heightened by pending legislative action that may allow routine administration of unproven stem cell therapies to patients in Italy.

«This new pathway will allow us to focus therapies on preserving healthy mitochondria within the beta cell to treat or prevent both type 1 and type 2 diabetes.»

Genetic analysis of cells allows therapies to be adapted to the type of cancer to be treated.

The number of extracted tumor cells allows conclusions to be drawn with respect to the success of therapy and the future course of the disease.

There are experiments in using stock market — like systems, in which people bet on ideas to answer seemingly unanswerable questions, like when terrorist events will occur or when stem cell therapy will allow a person to grow new teeth.

By performing a genome - wide screen in breast cancer cells, Dr. Oesterreich and her colleagues identified a gene called HOXC10 as one that the cancer seems to modify to allow continued tumor growth in patients whose cancer becomes resistant to traditional therapies.

«A safer route to ultrasonic therapy: Microbeads allow ultrasonic waves to stimulate cells more safely.»

«Uncovering why psoriasis recurs: Study identifies population of resident T cells that may initiate psoriasis and allow skin lesions to recur after therapy ends.»

That is, they contained multiple populations of cells, including the so - called JARID1B cells, which their research suggested was responsible for allowing tumors to survive drug therapy.

Under the proposed law, gene therapy will be approved only for the treatment of people with genetic diseases such as cystic fibrosis and will not be allowed in germ cells, where genetic alterations would be passed on to the next generation.

Because diseases such as cancer tend to evade detection by T - cells» receptors, allowing a tumor to grow unchecked, scientists have long sought «intel» on this process as a means of developing therapies that target malignant cells, but leave healthy cells alone.

A University of Colorado Cancer Center study published in the journal Oncogene used next - generation sequencing technologies to perform the most detailed DNA - based analysis to date of 25 commonly used bladder cancer cell lines, allowing researchers to match patient tumors with their closest genetic cell line match, and demonstrated genetic alterations that may make cells more or less sensitive to common therapies.

The moves also include # 50 million ($ 78 million) for a London - based «cell therapy technology and innovation center,» and # 60 million ($ 93 million) to develop the secure system that would allow researchers access to anonymized patient data from the National Health Service (NHS).

Instead, we administer a combination therapy to allow immune cells, which are capable of killing tumors, to see tumors that were previously invisible to the immune system.»

Checkpoint blockade therapy obstructs those signals, makes T - cells see the cancer cells as invaders again, and allows the immune system to do its job.

This is both a useful tool for giving us a better understanding of the genetic and epigenetic program controlling the self - renewal of stem cells, and on a practical side, it could allow us to inexpensively produce large numbers of immune cells, which could then be used for regenerative medicine or immune therapy.»

Chakravarti further notes that because GBM cells take up methionine much faster than normal glioma cells, positron emission tomography that uses methionine as a tracer (MET - PET) might help map GBM tumors more accurately, allowing more precise surgical removal and radiation - therapy planning.

Furthermore, this study also encourages the application of iPSC - MSCs as an exciting new therapeutic option for a range of immunological disorders and suggests that further study of the secreted factors may allow the construction of efficient cell - free therapies in the near future.

The complexity of the development of cells and gene therapy products are addressed by designing tailored studies to allow safety assessment of GTMPs and to fulfil GLP requirements and OECD principles.

To meet this end, CCIR members take advantage of resources offered by MD Anderson, including the CCSG Shared Resources, Immune Monitoring Core Laboratory and GMP Cell Facility, allowing them to follow the «bench - to - beside» approach to develop and improve cancer immunotherapy in the form of cellular therapy, a vaccine or targeting antibody, either alone or in combination with conventional therapies or newly developed therapies.

In parallel to this cell therapy application, keratynocytes and melanocytes derived from pluripotent stem cells will be used for pathological modelling of genodermatoses allowing identification of new disease - specific pharmacological treatments

Due to the high efficiency of establishing organoid models from different tissues and diseases, such as cancer, organoid technology allows the generation of large living biobanks of tumor organoids that are amenable for middle - throughput drug screens and may allow personalized therapy design, as a complement to cell line and xenograft - based drug studies (7,19).

Advances in research into the immunological evasion, metabolism and latency of metastatic cancer cells allow the identification of potential targets to test therapies.

Basically what was happening when you use a hematopoietic stem cell to correct an inherited metabolic disease is that through engraftment of that cell you are allowing that cell to become the replacement source for the missing enzyme or other factor - almost like a cellular form of gene therapy or, as I call it, «poor man's gene therapy».

Studying the molecular mechanisms that enable the metastatic cells to remain in dormancy for so long and then wake up and generate these macrometastases will allow us to develop therapies to prevent relapse, or, if metastasis occurs, to make it chronic or even stop it from spreading.

Selective targeting of the neurotransmitter that differentially affects brain cells that control the two distinct functions of the pancreas may allow for new medication therapies for conditions like diabetes, dyspepsia and gastro - esophageal reflux.

Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to Mcells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to Mcells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to MCells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to Mcells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to MLSP).

For cell therapy, automation can be used to increase the scale of cell culture operations (e.g., bioreactors replacing flasks) and allow the use of closed systems that can protect cell products from contamination with adventitious agents from the environment or operators themselves.

Utilizing cryopreservation allows for easier shipping and storage of the therapy, offering improved shelf life, potentially lower cost and the ability to ship the cells worldwide.

With those collaborations, our goal is to develop and eventually integrate the QuickGel platform into these closed cell therapy systems, allowing us to meet the scale and efficiency demands of the clinical bioprocess.

If approved after a 30 - day comment period, the new policy would allow the National Institutes of Health to fund researchers who want to put stem cells in early - stage animal embryos to study disease, possible therapies and organ transplants.

«The ability to direct a gene to a specific cell type and prevent expression in other cell types is a powerful new tool that allows us to bypass one of the most troubling safety concerns facing gene therapy,» said Michael Parmacek, MD, assistant professor of medicine at the University of Chicago and director of the study.

The patch allows for the same type of therapy — using pancreatic cells to regulate insulin — but the pancreatic cells remain outside the body in the smart patch.

CRCs, which were developed at Georgetown Lombardi, can keep both normal and cancerous cells alive indefinitely, allowing researchers to predict how therapies will work.

CAR therapy works by genetically modifying a person's own T - cells to express a synthetic receptor that allows cancer cell recognition.

Anti-viral therapies, such as the HAART regimen (Highly Active Antiretroviral Therapy), allow the T cell population a chance to recover and resume normal function.

The direct vascularization of the implanted cells is expected to allow for robust and consistent engraftment but will necessitate the use of maintenance immune suppression therapy.

Research from this team suggests that therapies targeting the vitamin D receptor will perhaps «unmask» the pancreatic tumors and allow the immune cells to reach them, creating the possibility that immunotherapies will be effective.

The system allows for pooling and testing of multiple cell lines simultaneously, and promises to accelerate the search for targeted therapies by better representing the broad genetic diversity of disease.

The exclusive, worldwide license, announced Sept. 14 by Mustang Bio, will allow a new type of CAR (chimeric antigen receptor) T - cell therapy to be tested in a clinical trial as a treatment for B - cell non-Hodgkin lymphomas.

Okyanos is proud to have been the first cell therapy facility to receive approval from the Bahamas National Stem Cell Ethics Committee (NSCEC) under legislation passed in 2013 which allows and regulates the use of patients» own adult stem cells in the treatment of certain chronic conditicell therapy facility to receive approval from the Bahamas National Stem Cell Ethics Committee (NSCEC) under legislation passed in 2013 which allows and regulates the use of patients» own adult stem cells in the treatment of certain chronic conditiCell Ethics Committee (NSCEC) under legislation passed in 2013 which allows and regulates the use of patients» own adult stem cells in the treatment of certain chronic conditions.

His gene therapy — delivering nanoparticles could transform patients into their own T - cell engineering labs, allowing them to be treated with reprogrammed T cells almost from the moment of diagnosis, skipping the waiting period and high cost of current approaches.

These two properties (self - renewal and pluripotency) confers human pluripotent stem cells a unique interest for clinical applications since they could allow the production of infinite quantities of cells for disease modelling, drug screening and cell based therapy.

In today's episode, Brian shares his own story and those of patients who have benefited from this therapy, along with the science behind why saunas work: how near - infrared incandescent light exposure stimulates the cells so that they can repair themselves, and allows the body to detox.