The resulting «map» of gene - drug interactions
allowed the researchers to accurately predict the responses of multiple human
cancer cell lines to different chemotherapy agents based on the
cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and
ovarian tumor
cells to common classes of chemotherapy treatment.
The book introduces the incessant menstruation hypothesis, which may
allow physicians to better understand and explain to patients why many serous
ovarian cancers may actually be originating from the fimbriated end of the fallopian tube and why endometrioid and clear
cell cancers may arise in association with endometriosis.