Sentences with phrase «allows zebrafish»

The shared gene allows zebrafish to sense water flow direction, and it also helps cells inside the human ear sense a range of sounds.

To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self - administer doses of hydrocodone, an opioid commonly prescribed to people for pain.

The Washington researchers have discovered some of the genes that allow zebrafish to regrow their tail fins, which could one day help humans regrow damaged body parts.

Not exact matches

Cortisol then effectively reduces levels of ACTH and CRH, completing the normal response that allows both humans and zebrafish to deal with stress.

That allows her to image the cells of awake, moving creatures, such as the flashing neurons of crawling fly larvae or the beating hearts of twitching zebrafish, without the problem of blurring when the animal moves.

Unlike humans, zebrafish larvae are transparent, which allowed researchers to watch their brains as they slept.

When the scientists inserted human colorectal cancer cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.

Zebrafish embryos have transparent brains, which allowed Peri and her team to track the microglia in real time under the microscope.

The team theorizes that zebrafish produce new heart - muscle cells, or cardiomyocytes, in response to injury, which allows them to regenerate undamaged heart muscle.

Zebrafish larvae and fluorescently marked immune cells allow researchers to track immune system activity in a model of retinal degeneration.

They developed a streamlined and fast, though inexpensive, method that allows direct access to a pure and vital population of zebrafish OPCs in less than 2 hours.

Dr. Lyons and his team used zebrafish to study the formation of myelin sheaths by oligodendrocytes because this laboratory animal is transparent at early stages of its development, which allows investigators to directly observe cells within the organism.

Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel development.

Building on traditional SIM technology, the iSIM allows real - time, 3 - D super resolution imaging of small, rapidly moving structures — such as individual blood cells moving through a live zebrafish embryo.

This is possible because the zebrafish retina contains cells called Müller glia that harbor a gene that allows them to regenerate.

«The zebrafish model allowed us to control those variables and see how bacterial strains tracked with inflammation.

In this case, zebrafish were critical for advancing our understanding of Jagged function in the liver, allowing us to devise new therapeutic strategies for Alagille Syndrome.»

«We use zebrafish to study Alagille syndrome because these vertebrates allow us to use experimental approaches that aren't possible with other disease models,» says Duc Dong, Ph.D., assistant professor in the Human Genetics Program at SBP and senior author of the paper.

Durdu, a PhD student in Darren Gilmour's lab at EMBL, found this behaviour in specific groups of cells in the zebrafish: the cells that will develop into the animal's «lateral line», a series of ear - like organs along the fish's flank that allow it to sense changes in water pressure.

Their preservation in the zebrafish allows us to visualize in this transparent genetic vertebrate model whether these variants are just neutral or if they disrupt the regulation of one the neighbor genes, possibly revealing the actual gene affected in AMD human patients.

Furthermore, the availability of transgenic lines of zebrafish exhibiting fluorescent blood vessels is allowing a rapid and precise analysis of vessels, thanks to the expression of a choral green fluorescent protein (G - RCFP) controlled by a promoter for VEGF - R2 [45].

In addition to this, the gene duplicates in zebrafish display strikingly different expression during the day - night cycle, presumably to allow efficient regulation of photoreceptor cells under dramatically different light conditions.

CRISPR not only allows researchers to create these animals faster and more precisely than before, but also to move beyond a relatively small menagerie of standard model species — fruit flies, mice, zebrafish — to create a Noah's ark of mutant dogs, pigs, primates and more.

The integration of a novel high spatiotemporal resolution volume imaging technique and a fast 3D tracking system allows capturing whole brain neural activities in a freely behaving larval zebrafish.