Sentences with phrase «along the chromosomes of»

And in any case «the gene» is a purely analytic sub unit of the greater and more significant complex that is the genetic code along the chromosomes of any organism.

Not exact matches

In order to isolate the 3D structure of the chromosome during metaphase, the authors used a combination of chromosome conformation capture technologies (3C, 5C and Hi - C) developed by the Dekker lab over the last decade to map the points of contact along the mitotic chromosome in different cell types synchronized to divide at the same time.

Previous work from Dekker and colleagues had shown that points of interaction along the chromosome influence gene expression and are the reason why different cell types are organized differently in three dimensions.

Dividing chromosomes are molecular Siamese twins: two bodies of genetic material joined along a stretch of DNA called the centromere.

The researchers discovered that the number of crossovers varied widely not just according to their position along the chromosome arm, but also from chromosome to chromosome.

They used a variety of population genetics and bioinformatics approaches to analyze genetic diversity along the chromosomes in multiple wheat varieties around the world.

Klingelhutz and his team immortalized immature precursor fat cells by adding in two genes from HPV (the virus that causes cervical cancer) along with a gene for part of an enzyme that controls the length of cells» telomeres — the pieces of DNA that protect chromosome tips from deterioration.

Earnshaw, along with colleagues from the National Institutes of Health and the University of Nagoya in Japan, have finally found a way around the problem and are now conducting the foundational research needed to build functional artificial chromosomes.

Using genetic analyses of more than 50 horse breeds, along with the pedigrees of three stallions that founded English Thoroughbreds, researchers traced the Y chromosomes of modern horses back hundreds of years.

Traces of how human beings had fanned out across the planet, acquiring superficial racial differences along the way, are written in our DNA and especially in the Y chromosome.

First, the researchers broke up the E. coli chromosome into small pieces that could be used to build a map of genetic landmarks along the DNA.

Boyko and his Cornell postdoc Laura Shannon then compared these dogs» genomes, as well as the genomes of more than 4500 purebreds from 161 breeds, at almost 189,000 spots along their chromosomes.

However, Pugh and Venters instead determined where along human chromosomes the proteins that initiate transcription of the non-coding RNA were located.

Extraneous structures like RNA and bound proteins are typically present along the length of chromosomes.

They found some 4600 tentative genes, many of which are identical to and in the same order along the chromosome as those of a common, typically harmless gut bacterium, Escherichia coli — a close relative.

«Brain anatomy differs in people with 22q genetic risk for schizophrenia, autism: Deletions or duplications of DNA along 22nd chromosome hint at biological underpinnings of these disorders.»

Right before a cell starts to divide to give birth to a daughter cell, its biochemical machinery unwinds the chromosomes and copies the millions of protein sequences comprising the cell's DNA, which is packaged along the length of the each chromosomal strand.

Human chromosomes each contain a single piece of DNA, with the genes arranged in a linear fashion along its length.

Plant geneticist Catherine Feuillet of INRA - UBP in Clermont - Ferrand, France, and her colleagues have isolated one of wheat's 42 chromosomes and made a physical map of it, placing more than 1400 molecular landmarks along its 995 million bases.

Repetitive DNA and similar sequences are a sequencer's nightmare because the sequence is generated in pieces that must be matched up correctly to figure out the order of the bases along each chromosome.

«In fact,» he says, «if you see... [this pair of symptoms], along with autism, it might predict the [chromosome --RSB- 16 deletion.»

«It was relatively easy to analyse and — along with the Y chromosome — allows us to go back in time, telling us about the genetic history of an individual.

Davis was able to analyze the resulting data on a chromosome - by - chromosome basis, along with the frequency of the identified variants and the function of variants associated with each condition.

These extra genes, along with the centromere and about 5 % of proximal Chr 17 are contained in a small extra chromosome derived from a reciprocal translocation.

After examining 33 variants of Pinot noir, Pinot gris and Pinot blanc, the researchers found that Pinot noir chromosomes often swap genes, occasionally losing genetic information along the way.

Completing this massive project, which is led by some of the authors of this study along with their collaborators around the world, will require many mating - type switches to consolidate the final synthetic chromosomes in a single strain.

According to our current understanding, cohesin is already loaded onto DNA (along the entire length of the decondensed one - chromatid chromosome) in telophase, i.e. only minutes after chromosome segregation, by opening / closing its Smc1 - Smc3 interaction site (or «entry gate»).

That poses an obvious problem during S phase: While DNA replication machineries («replisomes») zip along the chromosomes trying to faithfully duplicate the entire genome in a matter of just a couple of hours, they encounter — on average — multiple cohesin rings that are already wrapped around DNA.

Completion of eukaryal genomes can be difficult task with the highly repetitive sequences along the chromosomes and short read lengths of second - generation sequencing.

The BubR1 gene is important for protection of chromosome stability, along with Vitamin D. Magnesium is necessary to repair R - loop mutations.

As mitosis progresses, the microtubules align the chromosomes along the mid-line of the cell, then shorten and pull the chromosome pairs at their centromeres to opposite sides of the cell.

Complexes of DNA with lipids and proteins provide an alternative to viruses, and researchers are also experimenting with introducing a 47th (artificial human) chromosome to the body that would exist autonomously along side the standard 46 chromosomes, presumably not affecting their functioning or causing any mutations.

During recombination, the pairs of chromosomes divide in one or two places along their length and swap segments.

Consider the horizontal order of letters in the illustration below to represent different locations along a straightened - out chromosome, and the vertical arrangement to represent decreasing dominance.