The small feasibility trial, which involved 12 people with treatment - resistant depression, found that psilocybin was safe and well - tolerated and that, when given
alongside supportive therapy, helped reduce symptoms of depression in about half of the participants at 3 months post-treatment.
Interventions such as, psychoeducation intervention, brief psychoeducation intervention, family intervention, brief family intervention, cognitive behavioral
therapy, social skill training, life skill training, problem solving and
supportive therapy provided
alongside any other psychotherapies or pharmacology treatments, are considered for the review.