Sentences with phrase «alpha6 cytoplasmic domains»

Now Yuan et al. (p. 182, published online 27 May; see the Perspective Weyand and Iwata) have determined the crystal structure of the cytoplasmic domain of the human BK channel.

Cytoplasmic domains of members of the p24 family of putative cargo receptors were shown to bind to coatomer, the coat protein of COPI - coated transport vesicles.

Removing the cytoplasmic domain may distract the immune response and instead generate antibodies that target epitopes on Env that would not lead to protection.

Wang, H, Gai, Q, Yang, X, Li, Z, Linders, B, Santoro, S, Zutter, M. Role of the a1 and a2 integrin cytoplasmic domains in cell morphology, motility and responsiveness to stimulation by the protein kinase C pathway.

Glycosylated recombinant ecto - domain of gp41, from HXB2 strain, amino acids 546 - 682, produced in Pichia pastoris (without the membrane spanning and cytoplasmic domains).

281.2 Human CD4 with deletion of cytoplasmic domain, produces CD4 molecule truncated at aa394.

Increased levels of the cytoplasmic domain of Crumbs repolarise developing Drosophila photoreceptors.

Cell type - specific integrin variants with alternative alpha chain cytoplasmic domains.

The group first transduced a CD4ζ construct (CD4 extracellular and transmembrane domains fused with cytoplasmic domain of TCR CD3ζ chain linked to GFP — See Figure) into hESCs and hiPSCs using the Sleeping Beauty (SB) transposon system and positive clones selected for by antibiotic resistance, giving clones with strong CD4ζ - GFP expression (37).

Characterization of phosphorylation sites in the cytoplasmic domain of the 300 kDa mannose -6-phosphate receptor

Quantitative measurment of alpha6beta 1 and alpha6beta 4 integrin internalization under cross-linking conditions: a possible role for alpha6 cytoplasmic domains.

(A) Eph receptor - ephrin binding at cell - cell contact sites results in the dimerization / clustering of Eph receptor - ephrin complexes, and initiation of canonical signals through the receptor cytoplasmic domain.

Importantly, spreading and migration do not occur with cells expressing NG2 variants lacking the cytoplasmic domain of the proteoglycan, suggesting that interaction of NG2 with cytoplasmic ligands is required for these processes to take place.

Binding to the Eph receptors can also cause the ephrins, which have a cytoplasmic domain or a GPI - anchor, to transmit signals.

Not exact matches

The channel comprises an integral membrane pore, an integral membrane voltage sensor domain, and a large cytoplasmic region that confers Ca2 + sensitivity.

The assembly includes the cytoplasmic (T1) domain of the integral membrane α subunit together with the oxidoreductase β subunit in a fourfold symmetric T14β4 complex.

OX40 (CD134) is a 50 kD type I transmembrane glycoprotein in the TNFR superfamily, containing 3 full cysteine rich domains, and a relatively short cytoplasmic tail, and although a monomer it signals as a trimer when bound to OX40L, its known ligand in the TNF family.

4 - 1BB (CD137) is a 30 kD type I glycoprotein and again a typical transmembrane receptor in the TNFR superfamily, containing 4 full cysteine rich domains, and a relatively short cytoplasmic tail, and also signals as a trimer when bound to 4 - 1BBL, its known ligand in the TNF family.

Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA - binding domain and interaction with cytoplasmic retention factors