Eventually these smaller structures glom together to form plaques, but by then they have
already damaged brain cells.
Not exact matches
About 0.2 per thousand die (so are
already counted in the neonatal death statistics) so that leaves 3.5 per thousand probably
brain damaged.
We later found out that she was not sufficiently ventilated, and since we don't know what
damage she
already had, she had major
brain damage.
Already familiar with the seminal case of Phineas Gage, the hardworking, entrepreneurial 19th - century construction foreman who became an antisocial itinerant after a pointed rod pierced his skull and
damaged part of his
brain's emotional system, Damasio began to suspect that his patients» inability to be emotional was getting in the way of their reasoning.
The result is that Alzheimer's is generally detected very late in the disease process, if it is correctly identified at all — a blueprint for treatment failure, because the illness has
already irreparably
damaged the
brain.
«We expected an increase in the glutamate, because it is a chemical that causes
damage in high doses and we have
already seen
brain damage from sleep apnea.
There are a number of reasons why the trials may have failed, Hardy says, including the possibility that the antibody did not have high enough affinity for the particular forms of amyloid that do the most
damage in the
brain, or that the patients in the trials had
already experienced too much
brain degeneration to benefit.
Their compound, which is intended to repair
brain damage that has
already occurred, is a significant departure from current Alzheimer's treatments, which either slow the process of cell death or inhibit cholinesterase, an enzyme believed to break down a key neurotransmitter involved in learning and memory development.
This research points to inflammation as a potential early indicator of later
brain degeneration, but we can not say whether inflammation could be causing
brain shrinkage or if it is a response to other
damaging processes that might
already be underway.
Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you
Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much
damage), it's just «tolerable / liveable» enough (in terms of
damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general
brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the
brain is causal to how long we live; keeping
brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer
brain function means longer heavy
brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger
brain for their age), and both are correlated to MLSP).
A possible hypothesis for exactly how stress contributes is that it may cause a neurotoxic reaction in the
brain (primarily in the hippocampus) that leads to cell
damage and death in individuals who are
already vulnerable (due to genes or early environmental insult).
I founded a prolific
brain bank and after analyzing this vast collection, it became clear to me that by the time the first symptoms of AD manifest, the
brain has
already suffered considerable and irreversible
damage.
There are typical movements (chorea) that are associated with the disease, but they don't occur until significant
damage to the
brain has
already happened.
As if that were not challenge enough for a
brain that is
already struggling to metabolize fuel efficiently, AGEs themselves have been shown to be neurotoxic, likely by inducing apoptosis (cell death) and lipid peroxidation — a process that is especially
damaging to cells whose membranes are particularly rich in PUFAs.10, 33
You probably
already know some of the harmful health effects of these foods, but long term effects on your
brain are yet another... Trans fats — strongly inflammatory in your entire body including
damage to cell membranes throughout your body.
In light of some recent data, that showed
brain cell
damage due to anesthetics, we are even more aware of the potential toxicities, in addition to the
already known anesthetic risks.
Already good scenes somehow become even better, like the now famous riddles in the dark, which is brilliantly transformed into Bilbo and a
brain -
damaged orc literally building the answers out of Lego.