Sentences with phrase «also alters the cells»

But the cells also changed shape and other properties in the absence of the protein in ways that reduced the likelihood that they would travel away from the tumor — a sign that myoferlin not only changes genes in cancer cells, but also alters the cells» mechanical properties.

It appears that they can also alter cell function: a specific rice microRNA was shown to bind to and inhibit the activity of receptors controlling the removal of LDL — «bad» cholesterol — from the bloodstream.

Not exact matches

Also, it is well - known that body cells alter their extracellular environment by exchanging chemicals, generating heat, and so on.8

There is concern that THC may also alter brain cells during the time when a baby is experiencing significant brain growth.

Obesity also alters a person's metabolism, causing growth factor and hormone imbalances that help cancer cells thrive.

Although researchers have long known that genetic and epigenetic mechanisms can alter cells» shapes, recent work has shown that the reverse is also true.

According to Harkema, the DHA could be changing the way these cells, also known as macrophages, react to the silica in the lungs and somehow alter the immune system's response.

Not only do brain cells alter their connections, but additional neurons can also spontaneously form, a process called neurogenesis.

Changing the concentration also alters slightly which nerve cells fire a signal to the brain.

MYC also profoundly alters the oscillations of glucose metabolism and perturbs the consumption of glutamine, both essential metabolic molecules for cells.

The investigators also said the vaccine did not have the unwanted consequence of altering the number of T - regulatory cells, which suppress immune system responses.

The team also demonstrated the utility of the platform by applying it to examine a growth - modulating feedback circuit whose dynamics is qualitatively altered by circuit - host couplings and revealing the behaviors of a toggle switch across scales from single - cell dynamics to population structure and to spatial ecology.

Furthermore, besides offering valuable insight into the function of this novel RNA type, the researchers also believe that the findings will open new avenues for novel treatments in which cell - specific enhancer sequences can be targeted to alter gene expression.

They also tested to see if the drug was inhibiting production of normal RNAs in the cells, and found that it altered less than 5 percent of normal RNA sequences

When the research team used pharmaceuticals to inhibit one function of the endoplasmic reticulum (the building of so - called lipoprotein particles that will export fats out of the cell), the gene activation process was inhibited for many key genes and nuclear ruffling was also altered.

There's also a long - term risk from the gene therapy that we think is small, because we've genetically altered the T cells with a viral vector that's actually a modified, non-pathogenic form of HIV, the AIDS virus.

They also want to be able to insert more subtle mutations, such as those reported in HIV - resistant individuals, which could alter cell function just enough to confer resistance but without fully deactivating the gene and impeding cell function.

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

They determined that altering the expression level of LIGHT (a specific type of molecule that binds to a receptor site of another cell) and also lymphotoxin (LT) on T cells significantly impacted the cholesterol and triglyceride levels.

Besides restricting the amount of food a person can eat at one time, the procedure also seems to alter the properties of nerve cells.

But the protein can also change the genetic sequence of a normal cell, altering the body's blueprint and making mutations that cause cancers.

They also alter it clinically: It's now possible, in theory, to grow patient - specific pluripotent cells.

Il - 2 was one of the first cytokines («messenger» molecules that allow cells to communicate and alter one another's function) and proved to be a major tool not only for immunology but also for the discovery of all human retroviruses.

Stem cells and their tumorigenic alter egos cancer stem cells (CSCs) share many key properties, although CSCs are also posited to promote tumour growth, evolution, and drug resistance [1].

Zoghbi's lab also found that this altered ATXN1 gene sequence encodes a bulky, improperly folded protein that is toxic to brain cells.

«We have found that the same genes responsible for tamoxifen resistance in our animals are also turned off in human breast cancer cells that do not respond to the drug,» she says «Because these genes were epigenetically silenced — meaning they were not irreversibly altered, just switched off — it was possible to turn them back on.

Her current research is focused on discovering how normal and disease melanocyte cell states establish distinct regulatory DNA landscapes, and also determining how the combination of both genetic variation within these regulatory regions and environmental cell signals alter gene expression and normal cell function.

Cultures of senescent CD8 (+) T cells also show resistance to apoptosis, permanent loss of CD28 expression, altered cytokine profiles, reduced ability to respond to stress, and various functional changes.

We are also examining how gene expression and mitochondrial function is altered in human cells in the disorder known as Chronic Fatigue Syndrome or Myalgic Encephalomyelitis, in order to develop objective tests for the illness as well to identify causal factors.

On the other hand, using near - term nanotechnology to deliver into cancer cells siRNA or miRNA to alter cellular gene expression might also make it possible to «repair cancerous cells».

Also studied were cells taken from tail arteries of mice genetically altered to no longer express a protein called Rap1A, which the authors hypothesized would interact with a2C - AR.

In the different cell types of the body, different protein producing genes are active or inactive, and many medical conditions also depend on altered activity of specific genes.

We also demonstrate that ACTB haploinsufficiency leads to reduced cell proliferation, altered expression of cell - cycle genes, and decreased amounts of nuclear, but not cytoplasmic, β - actin.

High cortisol also alters tight junctions between cells such that small harmful substances may pass through the barrier.

Both types of BA were found be mutagens, meaning capable of altering genetic material, and both were also found to be aneugenic, meaning they affect cell division and lead to aneuploidy, an incorrect number of chromosomes.

It also tenaciously binds with tissue altering DNA, nerves, cell membranes, mitochondrial function.

Alcohol can also produce free radicals, which are unstable oxygen molecules that can alter DNA and cause cancer cells to develop.

The metals also altered gene expression, perturbed hormonal balance and accelerated the proliferation of the breast cancer cells.14

Many other cell cycle events have also been shown to be altered by ITCs.

It also suppresses viral RNA synthesis by altering key properties of the viral cell membrane (7).

They also speed up oxidative damage to cells and alter their behavior.

The communication between nerve cells may also be altered and severe alterations in the nervous system may also alter their behaviour.

She has also been awarded artist - in - residencies throughout California in Chandra Cerrito Contemporary, Oakland, Root Division, Jail / Cell AiR of Alter Space in San Francisco, Lucid Art Foundation in Inverness, Studio 110, Sausalito, The Bridge AiR in Los Angeles, as well as at The Studios of Key West in Florida and St.Mary's College of Maryland.