Sentences with phrase «also other tumors»

The shots trigger the animals» immune system to eliminate not only the injected tumors, but also other tumors in their bodies.

Not exact matches

It would also focus on research to identify other novel targets to attack a tumor.

Also, eating in a comparable manner to our precursors has been demonstrated on numerous occasions to offer stunning medical advantages, including counteractive action of most maladies of human progress, for example, tumor, coronary illness, Alzheimers, and other interminable conditions that are generally created by horrible eating routine and way of life.

Reducing STK17A also interfered with tumor cells» ability to move around and invade other areas of the brain.

Dr. Massagué is particularly interested in the ability of tumor cells to hug blood vessels, as he suspects this behavior may be essential for the survival of metastatic cancer cells not only in the brain but also in other parts of the body where metastatic tumor growth can occur.

These findings also have implications for treatment of cancer and other disorders, such as obesity, in which M2 macrophage cells play a regulatory role in tumor growth and fat deposition.

The findings also have potential uses for most other types of solid tumors, including those affecting the lungs and ovaries, because the same protein and enzyme are involved, François said.

Triple - negative tumors are also more likely to spread and recur than other types of breast cancers.

In pancreatic cancer, their activity boosts tumor growth and spread, and may also help suppress T cells and other immune elements that would otherwise attack the tumor.

On the other hand, our earlier work also showed that this enzyme acts to silence tumor - suppressor genes.

Uranium - 235 (U-235) is an isotope of uranium widely used for nuclear power generation and, like all other radioactive isotopes used in medicine, it has been also employed for diagnosis and treatment of diseased organs and tumors.

BRCA1 and 2, genes whose proteins are supposed to work as tumor suppressors and also repair DNA damage, were the first known risk factor genes for familial breast cancer as well as ovarian and other cancers.

«Additional studies are needed to see if these nanoparticles could also effectively deliver other antitumor genes for the treatment of brain tumors as well as systemic cancers.»

Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination with the wide applicability of F -18-FDG across a range of solid cancers, provides a stepping stone for clinical evaluation of this technology in other solid cancer types that also experience incomplete tumor resection due to close or involved margins.»

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

But the cells also changed shape and other properties in the absence of the protein in ways that reduced the likelihood that they would travel away from the tumor — a sign that myoferlin not only changes genes in cancer cells, but also alters the cells» mechanical properties.

«In the future, our models should provide robust tools to screen for therapies that impact tumor dormancy and metastasis, and should also provide a platform to solve other biological mysteries that underlie dormancy.»

«Our study reveals a previously unknown mechanism that we might be able to block to make tumors «visible» again to attacking immune cells, perhaps in combination with other immunotherapies,» says Miller, also an associate professor in the Department of Cell Biology.

The company is also developing techniques for analyzing other lung images, and images of cancerous tumors, to guide treatment using variations of the same technology.

They also tested other cancer lines — human cervical, lung and prostate cancers — and found that they responded to the patterned tumor environments in the same way.

And if fetal cells protect women from breast cancer, they might also safeguard against other tumors.

The Nakano lab is also working on brain metastases, tumors that spread into the brain from other parts of the body.

Although breast cancer was the initial focus and featured in the study published online today, the team has also conducted experiments with other types of solid tumors, with similar results.

The investigators also identified instances in which the genetic profiles of metastases were similar to those of only some cells in the primary tumor, suggesting that those cells were the source of the metastases, and other cases in which the genetic profiles of metastases from the same primary differed depending on their location.

Using cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in other tumor types.

In the process they induce inflammation; the cells also secrete other inflammatory chemicals, like interleukin - 6 and tumor necrosis factor - alpha, which are known to adhere to the endothelium of the blood vessels, an early event in atherosclerosis.

She also noted the targeting Msi in primary tumors significantly changed «the trajectory of progression by halting pancreatic cancer growth and improving survival,» inhibiting both cancer stem cells and other tumor cells.

A pituitary tumor could also induce milk production: «It would be the same reason — increased prolactin levels & mdashin the one case drug - induced, in the other due to a tumor or some other sort of neurological problem.»

Researchers are hopeful that the approach they used in this study of neuroblastoma may prove effective against some of the many other cancers also characterized by a surplus of MYC - family proteins in tumor cells.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

She notes that other researchers currently studying immunotherapies for glioma and other brain tumors should also consider doing the same.

Among these is BRG1 (also called SMARCA4) and the latest generation - sequencing technologies have extended these findings to other tumor types evidencing that BRG1 inactivation is widespread in cancer.

Tumor profiling can also reveal rare mutations and other changes that make some cancers unusually responsive to targeted drugs — knowledge that can be applied to patients with a variety of cancer types.

The team also found that these genes had different functions in promoting metastasis: One group encouraged growth of tumor cells in both breast and lungs, whereas the other only helped the new tumor thrive in the lungs.

It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

These tumors occur primarily on the skin but may also arise in other tissues where pigment cells are found.

«Agents that block the proteins — CDK4 / 6 inhibitors — have received Food and Drug administration approval for some patients with metastatic breast cancer, but they've also shown promise against others types of tumors in clinical trials.

The Genomics Facility also is working with other teams studying mutations in bladder cancer tumors; genetic mechanisms of sickle cell disease; viruses in Lake Michigan; and many other projects.

Two other researchers from Duke University were also presented with grant money for their contributions in brain tumor research in adults.

The fusion partner, the other part of the CAR, contains the business end — it's basically the engine that activates the T cell and tells it to kill the tumor cell that it's bound to, and also makes the T cell proliferate.

When possible, scientists will also collect and store other biological specimens such as leftover tumor or bone marrow samples.

In addition, the study, led by investigators in The Cancer Genome Atlas (TCGA) Research Network, revealed four novel tumor subtypes, while also identifying genomic similarities between endometrial and other cancer types, including breast, ovarian, and colorectal cancers.

Investigators also found genomic similarities between endometrial cancers and other tumor types.

Depending on characteristics such as how many tumor cells, blood vessel cells, and immune cells are touching each other, the tumor microenvironment can nearly triple the chance that a common type of breast cancer (estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study of 3,760 patients.

Two other neoadjuvants, doxorubicin and cyclophosphamide, also promoted metastasis by altering the tumor microenvironment.

The companies have launched a phase II trial of the antibody - drug conjugate, and are also testing it in other solid tumors, including ovarian and non — small - cell lung cancers.

We are also investigating targeting the normal source of HB - EGF, inflammatory cells, to determine whether HB - EGF alone or in concert with other cytokines produced by inflammatory cells is necessary for tumor formation.

Yongwon Choi, with Ralph Steinman and others, identifies a new tumor necrosis factor family member TRANCE (later called RANKL), [i] and subsequently demonstrates its role in the immune and bone system, and also in bone - residing cancers such as multiple myelomas.

Because cancer also appears as white on a mammogram, a high degree of breast density can make it difficult to spot tumors and other abnormalities.

Transplanting non-cardiac stem cells also increases the risk for tumor formation, as many of the cells turn into other cell types besides the target heart cells.