Sentences with phrase «alter cell behavior»

A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and process information at a systems level in order to alter cell behavior.

Not exact matches

We're funding researchers to investigate how drugs alter what genes are activated such that they modify the function of the cells, and how this, in turn, modifies the functions of brain circuits, and how that modifies behavior.

Because neural crest cells contribute to so many tissues in the body, altering their function could change an animal's behavior, appearance and biology, the researchers reasoned.

Even short - term blockages of this kind can lead to remarkable changes in the auditory system, altering the behavior and structure of nerve cells that relay information from the ear to the brain, according to a new University at Buffalo study.

A new study shows that these cells alter their behavior and structure when the animals» hearing is blocked.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

The snippet of plasmid DNA altered the cell's behavior, hijacking it and causing uncontrolled growth.

Altering the behavior of one cell or molecule can upset the entire system.

The team also demonstrated the utility of the platform by applying it to examine a growth - modulating feedback circuit whose dynamics is qualitatively altered by circuit - host couplings and revealing the behaviors of a toggle switch across scales from single - cell dynamics to population structure and to spatial ecology.

For research purposes, these cells hold an important advantage over those from blood in that they can be cultured without the use of artificial stimulants, which can alter the cells» behavior.

Mycoplasma compete with host cells for nutrients and can alter expression of receptors, ion channels, and growth factors resulting in changes to the cell line's growth and behavior.

Scientists keep finding new ways to play with cells and make them alter their behavior, even their identity...

The scientists can then turn different neurons in the striatum on and off to see how this alters the animal's behavior, revealing more about which cells do what in the brain.

Viral vectors are known to affect the transcriptional profile from target cells, altering their behavior and sometimes inducing apoptosis [6].

Mutations in these genes can substantially alter a cell's behavior.

''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).

Because DNA is encoded with the instructions for cell behavior, damaged DNA can alter cell processes including those that regulate growth and division.

They also speed up oxidative damage to cells and alter their behavior.

Her theories suggest that our mental perceptions transmit neurological signals that affect energy fields around the cells, which alter behaviors beyond behaviors inherited from our DNA — possibly explaining the practice of energy healing.