Not exact matches
Because neural crest
cells contribute to so many tissues in the body,
altering their function could change an animal's behavior, appearance and
biology, the researchers reasoned.
Attempts to describe and
alter this phenomenon have been difficult due to an imperfect understanding of the
cell biology involved.
Dr. Yamanaka's iPS discovery, first completed with animal
cells in 2006 and with human
cells in 2007, has since
altered the fields of
cell biology and stem
cell research — opening promising new prospects for drug discovery, personalized medicine and tissue regeneration.
Objective: To use innovative approaches of integrative
biology to unravel how lymphocytes process an array of molecular signals arising from contact with dendritic
cells, thereby better understanding the mechanisms that underlie immunity and how they are
altered in disease states.
My doctoral training, in the broad field of biochemistry, and
cell and molecular
biology, focused on mechanisms of glycosylation, which is
altered in diseases such as cancer and neuromuscular dystrophy.
New data and research approaches have created opportunities for researchers to study in detail many aspects of cancer
biology, including how the normal biological programs of
cell proliferation and death are
altered during cancer and how the immune system responds to tumors.
By utilizing the tools of
cell and molecular
biology, he studies the mechanisms by which chemical (for example, specific
cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by
cells and
alter their proliferation and specialization to either promote tissue growth or destruction.