Because DNA is encoded with the instructions for cell behavior, damaged DNA can
alter cell processes including those that regulate growth and division.
Not exact matches
One proposal that has received considerable scientific support has been to generate non-embryonic entities that can serve as a source of stem
cells through a
process termed
Altered Nuclear Transfer (or ANT).
We're surrounded by so much
processed food that our
cells are no longer capable of recognizing the food we eat because it has been
altered and genetically modified.
Carcinogens may cause cancer by
altering cellular metabolism or damaging DNA directly in
cells, which interferes with normal biological
processes.
To understand that
process, the Florida State group engineered a fruit fly to produce a mix of
cells, some with normal Lgl and some with the
altered version.
According to the head of the research group of chemoresistance and Predictors of tumor response and stromal environment ICO - IDIBELL, Alberto Villanueva, «tumor exosomes contain certain proteins (Dicer, TRBP and Ago2) able to
process microRNAs that can
alter the around the tumor
cells transforming them into tumoral
cells.»
Vitamin A and vitamin D are precursors to hormones that influence biological
processes by entering the nucleus of a
cell, binding to DNA, and
altering the transcription of certain genes.
The natural structures that exist either between
cells or within
cells are damaged during the freeze - thaw
process and hence the flavor or texture of the tissue is
altered.
Unlike genetic mutations that affect DNA and the genome, epigenetic markers turn genes on and off to regulate
cell processes, which if
altered may lead to disease, he explains.
Cell Phones
Alter Brain Metabolism: A 50 - minute phone call boosts metabolism in the brain regions closest to the antenna, including areas involved in language, decision making, and emotional
processing.
Jon Tilly, the director of the Vincent Center for Reproductive Biology at Massachusetts General Hospital in Boston, has been studying genetically
altered mice to better understand the
process of apoptosis, or natural
cell death.
A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and
process information at a systems level in order to
alter cell behavior.
Not only do brain
cells alter their connections, but additional neurons can also spontaneously form, a
process called neurogenesis.
Using lung cancer
cells and mice the scientists showed that the combination of two drugs, called TRAIL and a CDK9 inhibitor,
altered the molecular switches in the
cell suicide
process — forcing the cancer
cells to self - destruct.
Since HIV infection itself
alters epigenetic
processes in the immune system, the research team wondered whether a distinct DNA methylation profile, a major epigenetic modification where methyl groups are added to DNA, occurs in those with HIV associated - cognitive impairment and whether it exists in distinct immune
cell populations from the blood.
The team found they could replicate the healing abilities of the engineered mice by giving nongenetically
altered ones drugs that help activate certain metabolic
processes — the same pathway Lin28a stimulates — revving up and energizing
cells as if they were much younger.
When the research team used pharmaceuticals to inhibit one function of the endoplasmic reticulum (the building of so - called lipoprotein particles that will export fats out of the
cell), the gene activation
process was inhibited for many key genes and nuclear ruffling was also
altered.
Learn about the
process behind Penn's CAR - T
cell therapy, the first - ever cancer treatment that genetically
alters a patient's own immune
cells to target and destroy cancer
cells.
These so - called «living drugs» — injected T
cells genetically modified to better recognize and kill tumor
cells through a perpetual
process of
cell renewal and expansion — are revolutionizing cancer treatment, with the first two FDA approvals of such gene -
altering therapies occurring in just the last two months.
Pseudotyping is the
process of producing viruses with foreign envelope proteins and is frequently used to generate viruses with
altered cell tropism [Cronin et al., 2006].
During this
process, the virus
alters its appearance and our immune memory
cells struggle to recognise it, leaving the virus free to infect us once more.
Most recently, Dr. Jaenisch and his colleagues have shown that it is possible to isolate embryonic stem
cells without harming an embryo through a
process known as «
altered nuclear transfer.»
Objective: To use innovative approaches of integrative biology to unravel how lymphocytes
process an array of molecular signals arising from contact with dendritic
cells, thereby better understanding the mechanisms that underlie immunity and how they are
altered in disease states.
While the study suggests that cellular timing is a stubborn
process, the Thomson lab is exploring a variety of follow - up studies on potential factors that could help
cells alter their pace, Barry says.
The term has evolved to include any
process that
alters gene activity without changing the DNA sequence, and leads to modifications that can be transmitted to daughter
cells.
In a
process called oxidation, free radicals steal electrons from other molecules — fats, proteins,
cell membranes, and even DNA —
altering the fundamental structure of the affected molecule.
The current results suggest that better understanding the way in which mononuclear white blood
cell signaling
processes are
altered, net of effects on individual differences in
cell type composition, is promising as a mechanism by which protective parenting influences young adult pro-inflammatory tendencies among African American youth.