Sentences with phrase «alter gene products»

RNA editing, which can alter gene products without making changes to the genome, has profound potential as a tool for both research and disease treatment.

It will potentially eliminate the need to sequence around a newly discovered disease SNP to find the variant that actually alters the gene product, says NHGRI Director Francis Collins.

Not exact matches

This means that none of our food products have been altered at the gene level of the plant.

As a result, thousands of products containing foreign or altered genes have been eaten by millions of people.

These products are designed to alter the expression of target genes in the body, suppressing expression of genes associated with disease, or restoring expression of genes required for health.

Informally called jumping genes, these bits of DNA can replicate and insert themselves into other regions of the genome, where they either lie silent, doing nothing; start churning out their own genetic products; or alter the activity of their neighboring genes.

We report that a synonymous SNP in the Multidrug Resistance 1 (MDR1) gene, part of a haplotype previously linked to altered function of the MDR1 gene product P - glycoprotein (P - gp), nonetheless results in P - gp with altered drug and inhibitor interactions.

Among other things, we plan to include certain gene therapy products that permanently alter tissue and produce a sustained therapeutic benefit as part of the products that will meet the definition of being eligible to come under the pathway enabled by RMAT.