Sentences with phrase «alter the animal in»

Not exact matches

Minor episodes are added to explain details upon which Scripture is silent» the sons» wives are sent to distant lands to gather pairs of animals, and it is the giants, mentioned briefly before Noah appears, who provide the timber for the Ark» but nothing in the account is altered.

Say we have a population of animals which has to meet some new challenge offered to it by an altered environment; there may be some individuals in the population whose development is changed by the environment in a way which makes them better able to deal with the challenge — they show a capacity for adaptive modification.

Where is the clear line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from which a plentiful supply of insulin can be harvested, to (3) genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4) genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells which would otherwise have transmitted the disease to one's offspring?

In genetic modification (or engineering) of food plants, scientists remove one or more genes from the DNA of another organism, such as a bacterium, virus, or other plant or animal, and «recombine» them into the DNA of the plant they want to alter.

In animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDIn animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDIn human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDS.

The paper found that the mere presence of men in the lab induced such intense stress in rodents that it altered how the animals reacted to pain.

The door to creating designer species blew open in March when scientists announced the first successful demonstration of genetically altered animals passing their tweaked DNA automatically to their progeny.

Those drugs would have given the animals diarrhea, reduced their appetites and altered their gut flora in a big way.

Further studies in animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.

Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

The study, published in the journal G3: Genes Genomes Genetics, adds to a growing body of evidence suggesting that domestication alters animals» reactivity to stress.

In a separate experiment in anesthetized mice, the scientists «steered» the target area of the TI, without moving the electrodes on the animals» scalps, by altering the relative amount of current in each of the two high - frequency fieldIn a separate experiment in anesthetized mice, the scientists «steered» the target area of the TI, without moving the electrodes on the animals» scalps, by altering the relative amount of current in each of the two high - frequency fieldin anesthetized mice, the scientists «steered» the target area of the TI, without moving the electrodes on the animals» scalps, by altering the relative amount of current in each of the two high - frequency fieldin each of the two high - frequency fields.

One concern raised by the human brain organoid implants «is that functional integration [of the organoids] into the central nervous system of animals can in principle alter an animal's behavior or needs,» said bioethicist Jonathan Kimmelman of McGill University in Montreal.

Because neural crest cells contribute to so many tissues in the body, altering their function could change an animal's behavior, appearance and biology, the researchers reasoned.

Helfand speculates that Indy mutations might alter metabolism in a manner similar to caloric restriction, which extends life - span in mammals and other animals.

And the outcomes «may alter the view of hybridization in animals as some form of mistake,» comments Loeske Kruuk of the University of Edinburgh, «because it is now clear that we can not take the consequences for fitness at face value.»

More work is needed to determine whether the findings on rapamycin hold true in animal models of Leigh syndrome and other neurodegenerative diseases, and to ascertain how exactly rapamycin is altering the metabolism of the cells.

In addition, D4 causes tumors, reproductive problems, altered organ size and acts like a weak estrogen in studies of lab animalIn addition, D4 causes tumors, reproductive problems, altered organ size and acts like a weak estrogen in studies of lab animalin studies of lab animals.

In total, 506 different proteins were found to be altered in nerve tissue from horses with grass sickness, compared with animals that had died from other causeIn total, 506 different proteins were found to be altered in nerve tissue from horses with grass sickness, compared with animals that had died from other causein nerve tissue from horses with grass sickness, compared with animals that had died from other causes.

We know that exposing animals in utero, or during the infantile period, or puberty or pregnancy can alter the breast responsiveness and change what may happen later on.

(Update, 9:26 pm Statement from New Iberia:» Nothing in the videos alter the fact that the New Iberia Research Center is in compliance with all federal standards and guidelines regarding the care and use of animals, as determined by the U.S. Department of Agriculture, the Food and Drug Administration, and the Centers for Disease Control.»)

Because Zika typically has trouble establishing infections in mice, the researchers used animals that were genetically altered so that they could not produce interferon, a key immune system signaling molecule, thus dampening the animals» immune response to the virus.

The deactivation of specific PFC regions significantly altered the performance of the animals: The inhibition of regions in the infralimbic cortex (IL) or the orbitofrontal cortex (OFC) impeded the ability of the rats to react to external signals.

Landfills have altered animal behavior, distribution and abundance around the world in a variety of ways, from increasing abundance of storks to fragmenting populations of bears.

It also remains unclear how knocking down expression of certain genes in zygotes via sperm miRNA leads to altered stress response in adult animals and altered gene expression in the brain.

It turns out that Maf1 plays a much more significant role in a whole animal: altering how the animal stores fat.

Research in animals has hinted that antidepressants such as Prozac and Lexapro, from a class of drugs called serotonin reuptake inhibitors (SSRIs), may alter certain aspects of fetal neurodevelopment.

The chemicals, considered hormone disruptors, have been linked to health effects in animal tests and some human studies, including altered male genitalia, attention and learning problems and asthma.

Interestingly, women with lupus display autoantibodies and cytokines, which — when studied in animals — have been shown to alter fetal brain development and induce behavioural irregularities in offspring.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons the presence of a magnetic field through the altered behavior of the animals.

The research is helping scientists better understand how animals survive under drastic temperature changes, information that's critical in a world being altered by climate change.

Debate over whether genetically altered animals can be patented in Europe took a new turn last week after the European Patent Office published its patent for the Harvard «onco - mouse».

Animals with gene mutations that significantly alter their circadian rhythms have shorter life spans, and circadian rhythm sleep disorders in humans can have profoundly negative effects, including increased risk for obesity, depression, cardiovascular disease and cancer.

In a related research project, Timiras injected young and old rats with overdoses of adrenocortical hormones to test how the treatment altered their brain structure; the brain hemorrhaged and swelled, more so in the elderly animalIn a related research project, Timiras injected young and old rats with overdoses of adrenocortical hormones to test how the treatment altered their brain structure; the brain hemorrhaged and swelled, more so in the elderly animalin the elderly animals.

That particular protein is present in all plants and animals, so it can be altered in crop species without resorting to a transgenic approach, Li said.

This would allow us to alter RNA in a living system and track what effect those alterations are having on the cell or animal as a whole.

Although the substance did not provoke the symptoms seen in the previous experiment, Hsiao says that the animals» altered response suggests that the substance could play a role in the disorder.

«Perhaps something in the cooking process altered the biochemical requirements for maximal access to nutrients as well as the need to process the natural toxins found in plant and animal foods.»

Interestingly, Xiong et al. further showed that the GDF15 regimen altered food preferences in mice — leading the animals to opt for lower calorie chow when offered a choice between standard food and an extra-rich condensed - milk diet (untreated mice gorged themselves on the high - calorie eats).

The effect of citronella was discovered during research into how odours alter animal behaviour conducted at the College de France in Paris.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons in the presence of a magnetic field through the altered behavior of the animals.

From a conservation and management perspective, this means that when studying animals that may not live in obvious groups, we need to still consider traits within things like social neighbourhoods because these traits can alter how an animal responds to selection pressure.»

In animal models, maternal diet alters offspring body composition, accompanied by epigenetic changes in metabolic control geneIn animal models, maternal diet alters offspring body composition, accompanied by epigenetic changes in metabolic control genein metabolic control genes.

Studying these symptoms earlier in the animal model gives researchers more time to monitor the progression of the disease as well as assess the efficacy of potential therapeutics and to determine if and when the course of the disease could be altered.

Howard Hughes Medical Institute researchers in that lab have discovered how to alter the animals» memories by turning on neurons in the brain that are associated with the memories and updating them with new information.

For biologists in the laboratory, this is a way to probe a geneâ $ ™ s function by making an animal with its genes altered in a certain way.

Examples of funding areas include but are not limited to molecular genetic analysis of relevant neural circuit assembly and function; genetic and epigenetic research; animal models created by genetically altering neural circuits; and testing of new chemical entities that might be used in animal models as exploratory treatments.

Wang and his colleagues discovered that in animal models, recurrent cycles of too much alcohol consumption, followed by alcohol abstention, actually altered the strength of these neural branches.

According to experiments by BIOACID scientists, rising temperatures and carbon dioxide concentrations might alter the composition of fatty acids in the animals» bodies.

Advances in optical imaging and optogenetics combined with electrophysiological recordings enable Albeanu and colleagues to monitor and / or alter patterns of activity at unprecedented synaptic and millisecond resolution, in real time, as animals are engaged in various behaviors.