Sentences with phrase «alteration in gene expression»

One of the mechanisms driving alterations in gene expression is epigenetic change, where the female is able to change her offspring's genome to cause certain genes to be expressed differently.
Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.
However, follow - up revealed a different natural history to that of childhood autism, with these children no longer fulfilling criteria for autism, with mild cognitive impairment, low empathy and conduct problems prevailing in adolescence.2 Animal models suggest a possible epigenetic mechanism for this, with environments of profound neglect associated with alterations in gene expression as a result of DNA methylation.3
AAEM pointed to numerous animal studies that showed oxidative stress, altered structure and function of the liver, intestinal damage, disruption of the immune system, increased cell growth and hundreds of alterations in gene expressions.
Epigenetics refers to an alteration in gene expression that occurs without a change in the sequence of DNA molecules.
Alu elements affect the genome in several ways, causing insertion mutations, recombination between elements, gene conversion and alterations in gene expression.
This will be achieved by exposing the coral to seawater with high calcium concentrations to induce an alteration in gene expression profiles, identified using a DNA microarray analysis.
We are examining the biochemical effects of these mutations on the splicing process as well as studying the alterations in gene expression and alternative splicing caused by these mutations.
Age - induced accumulation of nuclear DNA damage, decline in mitochondrial function and alterations in gene expression have been thought to contribute to aging.
They cause an alteration in gene expression, leading to a suppression of key mitochondrial enzymes, like carnitine palmitoyltransferase — which finally solves the mystery of why those eating vegetarian have a 60 % higher expression of that fat - burning enzyme.
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