Sentences with phrase «alterations in gene expression caused»

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

Not exact matches

Using clinical, genetic, and gene expression data as filters to distinguish genes whose copy number alteration causes cancer from those for whom copy number changes are incidental, the team whittled down their list from 14,000 to a more manageable number, each of which they systematically tested using genetic experiments in animals.

One of the mechanisms driving alterations in gene expression is epigenetic change, where the female is able to change her offspring's genome to cause certain genes to be expressed differently.

Epigenetics is the study of changes in organisms caused by modifying gene expression — by alcohol, for example — rather than alteration of the genetic code itself.

Combination of methamphetamine and HIV - 1 gp120 causes distinct long - term alterations of behavior, gene expression, and injury in the central nervous system.

Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expressionexpression

The causes of the widespread differential expression of non-coding RNAs in malignant compared with normal cells can be explained by the location of these genes in cancer - associated genomic regions, by epigenetic mechanisms and by alterations in the processing machinery.

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia (ALL), according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

They cause an alteration in gene expression, leading to a suppression of key mitochondrial enzymes, like carnitine palmitoyltransferase — which finally solves the mystery of why those eating vegetarian have a 60 % higher expression of that fat - burning enzyme.