Sentences with phrase «altered cell state»

Not exact matches

To understand that process, the Florida State group engineered a fruit fly to produce a mix of cells, some with normal Lgl and some with the altered version.

Within a decade, we should be able to use these technologies to read and alter the state of neurons for an enormous fraction of the cells in human brains.

In the scientific article «Histone mutations separate R loops from genome instability induction» published in Molecular Cell, the researchers state that RNA joins with DNA by chance or because of a disease, the structure of the chromatin, the protein envelope of the chromosomes is altered, causing breaks in the DNA.

They found that the histone code, which alters the transcriptional state of the gene, changes over time as stem cells differentiate into blood vessels in response to a stimulus.

Previously, True and Whitehead Institute Director Susan Lindquist reported that a particular yeast protein called Sup35 somehow altered the metabolic properties — or phenotype — of the cell when it «misfolded» into a prion state.

So this language in effect means alterations of embryonic cells can not be done in the United States if there is any intent to treat a human being, including implantation of an altered embryo into a woman's uterus.

Three leukemias that affect as many as 100,000 people in the United States are all caused by acquired mutations that alter a specific enzyme controlling blood cell proliferation, according to new...

Melanocytes respond by altering gene transcription, and these changes in gene expression profiles result in easily quantifiable phenotypes such as modified pigment production (a hallmark of melanocyte differentiation state) and changes in morphological cell properties.

Objective: To use innovative approaches of integrative biology to unravel how lymphocytes process an array of molecular signals arising from contact with dendritic cells, thereby better understanding the mechanisms that underlie immunity and how they are altered in disease states.

From other papers I would like to highlight the one by M. Mehrshad and enigmatic SAR202 cluster, the one by A. C. Lehours and biogeographic patterns of aerobic anoxygenic phototrophic bacteria and the one by E. M. Llufrio and how fluorescence activated cell sorting introduces oxidative stress and alters the metabolic state of cells.

Her current research is focused on discovering how normal and disease melanocyte cell states establish distinct regulatory DNA landscapes, and also determining how the combination of both genetic variation within these regulatory regions and environmental cell signals alter gene expression and normal cell function.

Thus we examined whether FGF signalling could alter the dynamics between the V + and V − states within the S + population by culturing HV cells in the presence of the FGFR inhibitor PD173074 [41] for 48 h.

Manipulation of either FGF signalling or Nanog expression levels can alter the ratio of cell types present in this state and single Venus positive or negative cells can regenerate this equilibrium with apparently identical kinetics under self - renewing conditions.

Changes in the CSC fraction in relation to non-CSC could be due to altered proliferation, self - renewal, or cell death rates or dedifferentiation of non-CSC into a less mature cell state any of which would result in a change to the balance between the 2 compartments (44, 45).

Tumor cells constantly alter their metabolic state in response to oncogenic stimuli, nutrient availability, and interaction with immune cells however the precise regulation that precedes the metabolic alteration is poorly understood.

Growth of the synaptic web is utterly different from concrete physical things which maintain cells» metabolism and alters their structural and functional energetic state.