When implanted into mice, the pool of
altered cells maintained their gene edits long - term, with no signs of side effects.
Not exact matches
The stem
cells that
maintain this lining, called colonic stem
cells, were
altered.
Studies in diabetic rodents suggest that diabetes may
alter the intestine's mucosal lining, which is
maintained and regenerated by intestinal stem
cells; however, little is known about how this occurs and whether it is relevant to humans.
For example, domestication had seemingly
altered 13 places near a gene called SOX2, which helps
maintain cells destined to become part of the nervous system.
If a
cell fails to produce the ultraconservated RNA, microRNA gets
altered and hundreds of genes that should
maintain cellular balance does and thus contributes to the formation of human tumors,» concludes Manel Esteller.
When using a well established model of colorectal cancer, the researchers observed that dietary emulsifier consumption was sufficient to make the animals more susceptible to developing colonic tumors because this created and
maintained a pro-inflammatory environment associated with an
altered proliferation / apoptosis (
cell death) balance.
Changes in DNA methylation in brain
cells has been an extremely active research area since these epigenetic changes were shown to
alter the expression of genes needed to form and
maintain long - term memories.
Growth of the synaptic web is utterly different from concrete physical things which
maintain cells» metabolism and
alters their structural and functional energetic state.