They include reduced lymphocyte repertoire, increasing clonality and increasing autoreactivity.5, 7,8 Recent work has focused on intrinsic cell defects, which
alter T cell activation threshold, induction of
cellular senescence and
differentiation into short - lived effector or long - lived memory cells.
«A «deficiency» of polyunsaturated fatty acids leads to
altered rates of
cellular regeneration and
differentiation, a larger brain at birth, improved function of the immune system, decreased inflammation, decreased mortality from endotoxin poisoining, lower susceptibility to lipid peroxidation, increased basal metabolic rate and respiration, increased thyroid function, later puberty and decreases other signs of estrogen dominance.