Sentences with phrase «altered gene»

A small Norwegian study suggested that yoga's many healthy benefits might come from its ability to alter gene expression in immune cells.

Doctors generally do not treat disease by altering genes in people or changing how they work.

Typically, these green fluorescent proteins are used to monitor the activity of altered genes.

Cells respond to diverse stimuli by altering gene activity.

By altering the genes in male mosquitoes, researchers have just impaired the ability of these insects to reproduce.

This cellular thermometer is sensitive enough to react to changes in body temperature between 36 and 38 ° C with altered gene expression.

But today's lesson is about a newer technology, a means for altering the genes of any organism — and, potentially, its offspring.

Scientists had altered their genes so that they lacked a certain type of nerve cell in their spinal cords.

This poor parenting actually alters genes controlling the production of stress hormones.

RNA editing, which can alter gene products without making changes to the genome, has profound potential as a tool for both research and disease treatment.

Scientists reported selectively altering genes in viable human embryos for the first time this year.

Through gene profiling, they were able to discern that absence of gut bacteria altered genes and signaling pathways involved in learning, memory, and motor control.

The underlying genetic basis of many of these differences may be altered gene expression.

We've found loneliness is associated with altered gene - expression, which makes you more susceptible to viruses, a correlation that has been shown in humans and animals.

Through a series of tests, the team found that mutations were altering gene activity through two distinct mechanisms — both in the same «direction,» by disrupting the gene.

However, altering genes in human embryos can have unpredictable effects on future generations.

Beebread contains p - coumaric acid, which alters gene expression and contributes to the honey bees» developmental fate.

In addition, the DHA and EPA found in fish oil have a powerful ability to enhance the metabolism and increase fat burning by positively altering the gene functioning through various mechanisms which include changing the makeup of cell membranes, altering the transcription of genes and influencing the levels of calcium within the cells.

The researchers further found that miR - 486 is itself regulated by the tumor - suppressor gene p53, the most frequently altered gene in human cancers, and that activity of miR - 486 is partially dependent upon functional p53.

«This gave us evidence that, while anti-cancer drugs are effective in preventing tumor cells from replicating, they can also alter gene expression simultaneously as they inhibit DNA replication, a phenomenon that has not been investigated widely,» she said.

PTEN is reportedly the second most commonly altered gene in human cancers.

Melanocytes respond by altering gene transcription, and these changes in gene expression profiles result in easily quantifiable phenotypes such as modified pigment production (a hallmark of melanocyte differentiation state) and changes in morphological cell properties.

The male offspring of mothers fed the high - fat diet showed altered gene expression in the hippocampus which persisted through adulthood.

Rassoulzadegan stumbled upon her rodent scofflaws after altering a gene in gray mice so that their feet and the tips of their tails turned white.

New research has found that the pharmaceuticals, which are frequently showing up in U.S. streams, can alter genes responsible for building fish brains and controlling their behavior

The researchers discovered that this receptor mutation profoundly altered gene expression in neurons receiving dopamine at distal sites in the brain, specifically in the prefrontal cortex.

That explanation came later, with the burgeoning new field of epigenetics — the study of how the external environment can alter our genes throughout life, and even be passed on to future generations.

The MU researchers altered the gene to enable more efficient transfer of the nNOS gene to mouse hearts.

What is known from global studies is that exposure to biologically active compounds, even at ng / L concentrations, can impact endocrine systems in nature and manifest as negative impacts like altered gene regulation, the presence of mixed reproductive tissues (intersex) and skewed sex ratios.

For this compilation, I've emphasized publications in which whole - genome or exome sequencing was employed to multiple tumors or cancer cell lines, with the goal of identifying significantly altered genes or pathways in malignant cells.

Unless healthy gut flora is reestablished in early infancy, the child may suffer permanently altered gene expression and altered behavior; and may be prone to vaccine damage.

In fact, the beneficial bacteria strains in milk kefir actually repopulate the digestive tract, whereas the cultures added to yogurt work more behind the scenes to positively alter gene expression and reduce inflammation.

It can weaken one's immune system, heighten emotional responses, and even alter gene expression.

For now, Stadler's team wants to focus on the regions in which it found altered gene numbers to see how the CNVs affect gene and protein functions.

Surprisingly, RNAs in these various guises shut down and otherwise alter gene expression.

Decreased cohesin in the brain alters gene expression leading to the disruption of neuronal network formation

As for altering gene structures, Watson was confident that that would not be done for «trivial reasons.»

Altered gene imprinting at other times has been associated with developmental disorders and cancer.

«Rare variants alter gene function but occur at low frequency in a population.

It studies altered gene functions that are not due to a change in the DNA sequence, but may nevertheless be inherited.

Since the Lung Cancer Mutation Consortium trial began in 2009, many patients are now tested for mutated or altered genes before treatment.

Such tags alter gene activity without changing the information in genes.

In a paper last August, researchers reported that the virus (Zaire ebolavirus) was altering its genes almost twice as fast as it had during previous Ebola outbreaks in Central Africa (SN: 9/20/14, p. 7).

Gene editing could include altering genes in one person — say to treat leukemia in one patient or make a cosmetic change — but, more controversially, it could also include making changes to the germ line that would then alter the genome for an individual's children, grandchildren and the following generations, with potentially unknown repercussions.

Others have tracked the first few hours of the embryonic development of sea urchins and other organisms with the goal of seeing how various transcription factors alter gene expression over time.

Synthetic incompatibility has applications in controlling or eradicating invasive species, crop pests and disease - carrying insects as well as preventing altered genes from escaping from genetically modified crops into other plant populations.

The toxin did not appear to be altering gene sequences; instead, Skinner and colleagues found, vinclozolin was somehow causing other chemical groups to latch onto certain genes, changing their expression (Science, 3 June 2005, p. 1391).

They found that ONC201 alters the gene expression of cancer stem cell markers and signaling pathways prior to killing the tumor cells, providing pharmacodynamic biomarkers of response.

McClellan and his colleagues found that the mutations were much more likely to alter genes involved in brain development.