Newly developed approaches that use CRISPR / Cas9 gene editing technology can generate offspring that carry copies of
the altered gene on both chromosomes — a phenomenon called super-Mendelian inheritance that, in theory, should quickly convert an entire population.
Not exact matches
Individuals with one
altered gene had longer telomeres, the caps
on the ends of
chromosomes that wear away as we get older, and appeared to be protected against diabetes, the researchers report.
Right: By
altering both
chromosomes,
gene drives ensure both copies of the
altered gene are inherited, leading to a 100 percent chance of passing it
on.
These could
alter the expression of
genes on other
chromosomes, and might be partly responsible for behavioural differences between the sexes, says Rissman.
The evaluation using biostatistical methods revealed a clear connection with an
altered gene: ISL1, which is located
on chromosome five.
Miller said that the viral receptor
gene, HYAL2, was located
on a region of human
chromosome 3 that is frequently
altered in lung cancers.