"Altered metabolism" refers to changes in the way our body breaks down and uses nutrients, such as carbohydrates, fats, and proteins. It implies that the normal metabolic process is somehow modified, which can affect various aspects of our health and bodily functions.
Full definition
The surgery also changes the community of bacteria living in a patient's gut, which may drive weight loss and could
even alter metabolism.
Cancer cells
alter their metabolism in the interest of sustaining rapid growth, and high levels of PHGDH appear to drive such metabolic change.
What's most surprising is that even after controlling for fiber intake, those on plant - based diets still had significantly lower risk, leading the researchers to suggest that meat itself may increase the risk of diverticular disease «
by altering the metabolism of bacteria in the colon, which could lead to a weakening of the colon wall....»
This study will verify that tumor cells rely on lipid metabolism for growth, and determine if tumor
cells alter the metabolism of fat cells to obtain cellular nutrients and accelerate tumor cell lipid metabolism.
Energy restriction
alters your metabolism as your body has to adapt to the new (lower) amount of energy available - thus slowing your metabolism to conserve energy and storing energy as fat to be used later.
By painstakingly analyzing long lists of metabolites, McDonald and Vanderbilt undergraduate student Anna Word discovered that distant
metastases altered their metabolism by consuming excess amounts of glucose and directing it through the pentose phosphate metabolic pathway.
That research showed that mice on a normal diet who were exposed to low doses of antibiotics throughout life, similar to what occurs in commercial livestock, packed on 10 to 15 percent more fat than untreated mice and had a
markedly altered metabolism in their liver.
New research suggests the bacteria that cause
tuberculosis alter their metabolism to combat exposure to antimicrobials, and that these metabolic «escape pathways» might be neutralized by new drugs to shorten the troublesome duration of therapy.
Embryos from overweight and obese women also
showed altered metabolism of some amino acids, which are often described as the «building blocks» of our cells, muscles and tissues.
We already have, since some approved drugs intervene in cancer cells» specific metabolic needs, but research into
how altered metabolism promotes cancer is leading to more directed efforts.
IDH is mutated early in the development of those cancers, supporting the theory that cancer cells evolve
toward altered metabolism, «selecting» mutated genes as they develop.
«Maybe the normal versions of oncogenes and tumor suppressors originally evolved to regulate metabolism, and their
mutations alter metabolism in ways that inevitably become oncogenic,» says Thompson.
The former only restricts carbohydrates, while maintaining a sugar burning metabolism, whereas the latter shifts the body into a state of nutritional ketosis, which
completely alters the metabolism.
This is still a dose - dependent effect and these cats were somehow more susceptible (e.g. due to
altered metabolism due to age), or
Toxins also interfere with digestion, slow bowel function and
even alter metabolism, leading to weight gain.
Two decades of intensive pursuit have yielded a range of drugs that
alter the metabolism of amyloid - β, but these have yet to fulfil expectations.
Today I'm sharing my favourite mood foods that have been proven to
alter your metabolism and brain chemistry, ultimately affecting your energy level and mood.
Components of indoor dust may signal human fat cells to grow and may
alter metabolism, potentially contributing to weight problems, researchers report July 14 in Environmental Science & Technology.
As such,
the altered metabolism in the bone cells caused the mice to have a beneficial whole - body glucose turnover and a lean body.
The authors suggest two pathways by which hypobaric hypoxia might increase the risks of suicide and depression: by
altering the metabolism of the neurotransmitter serotonin and / or through its effects on brain bioenergetics.
Helfand speculates that Indy mutations might
alter metabolism in a manner similar to caloric restriction, which extends life - span in mammals and other animals.
More work is needed to determine whether the findings on rapamycin hold true in animal models of Leigh syndrome and other neurodegenerative diseases, and to ascertain how exactly rapamycin is
altering the metabolism of the cells.
Endocrinologist Robert Schwartz of the University of Colorado Health Sciences Center in Denver suggests how diet could factor into the equation: calorie restriction — which is known to reduce insulin resistance — might
alter metabolism by influencing the types of fat that calories build.
The research is part of a growing effort among cancer researchers worldwide to create treatments that target
the altered metabolism of cancer cells.
As a result, cancer cells must
alter their metabolism to provide the additional fuel needed for them to survive, grow and spread.
Further research showed that the WWOX gene plays a role in
the altered metabolism of cancer cells which are known to use glucose differently to normal cells.
The cells in which mtDNA was reduced had
altered metabolism and their structure appeared disorganized, more like that of a metastatic cancer cell.
The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
Now, Salk scientists have pinned down how signals from this microenvironment encourage pancreatic tumors to grow by
altering their metabolism.
Infants with PWS fail to thrive and have
altered metabolisms and trouble feeding.
Melanin - concentrating hormone 1 receptor - deficient mice are lean, hyperactive, and hyperphagic and have
altered metabolism.
He also contended that
this altered metabolism was the cause of cancer, and for decades that notion was at the center of cancer research.