Not exact matches
After reading Morrison's work, Siddaraju Boregowda, a
stem cell researcher at the Scripps Research Institute in Jupiter, Florida, was reminded of genetically
altered mice that don't gain body fat or develop diabetes, even when fed high - fat diets.
Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow
stem cells from
mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number
altered was modest.
She has generated multiple genetically
altered mouse strains to facilitate lung
stem cell analysis in vivo.
The finding is based on studies of
mice with
altered levels of the growth factor PDGF in neural
stem cells, which play a key role in the development of the eye.