And in 2012, they uncovered the first evidence that sleep apnea influences epigenetics,
altering gene expression without changing an individual's DNA.
Monitoring mRNA could tell scientists a great deal about which genes are being expressed in a cell, and tweaking the translation of mRNA would allow them to
alter gene expression without having to modify the cell's DNA.
«This is the first example of how early environment can
alter gene expression without mutating the gene itself,» Jirtle says.
The study examined DNA methylation — an «annotation» of DNA that
alters gene expression without changing the genomic sequence itself — in a group of diverse Latino children.
Not exact matches
The two - step process of TILT — getting sick upon toxicant exposure and failing to get well — may be driven by epigenetic changes, which occur when the environment
alters the
expression of
genes without changing the core DNA code itself.
«Margery's experiments showed that the NS1 protein can
alter expression of Hedgehog target
genes on its own,
without other viral proteins,» said Bier, professor and newly named holder of the Tata Chancellor's Endowed Professorship in Cell and Developmental Biology.
For the first time, scientists have improved how a crop uses water by 25 percent
without compromising yield by
altering the
expression of one
gene that is found in all plants, as reported in Nature Communications.
DNA methylation and other epigenetic alterations — chemical changes to DNA that can
alter a
gene's
expression without affecting its protein - coding sequence — may underlie some of the lasting biochemical havoc, Ghanei says.
The presence of such sequences could provide organisms with a way to modify their
gene expression without altering the actual coding sequence of
genes.
The activated AHR / NuRD complex
altered the
expression of differentiation - specific
genes that control the first two developmental decisions
without affecting the pluripotency program.
Surprisingly, they did this
without altering the
expression of
genes thought to be involved with the calcification process.