Sentences with phrase «altering target sequences»
Immunizing drives could block the spread of unwanted gene drives by preemptively altering target sequences.
http://science.sciencemag.org/ Not exact matches
Examples of potential problem include unforeseen immune reactions or altering the wrong sequence of DNA — so - called off - target effects.
Changing the disease target didn't require developing or identifying a whole new drug, just altering the mRNA sequence.
As they become better at the task, the software adapts to alter the orientation of the patterns, place them closer to the target, or speed up the sequence.
The larger scale Cancer Genome Atlas study provided the information needed to alter proteins or RNA sequences that may act as «drivers» for prognostic biomarkers or therapeutic targets.
Furthermore, besides offering valuable insight into the function of this novel RNA type, the researchers also believe that the findings will open new avenues for novel treatments in which cell - specific enhancer sequences can be targeted to alter gene expression.
A series of genetic analyses confirmed that the DNA target sequence had been altered in the transgenic plants, with either DNA insertions or deletions in both copies of the DFR - B gene (so - called bi-allellic mutants).
«Since MCR works by targeting specific DNA sequences, in cases where diseased cells have altered DNA as in HIV - infected individuals or some types of cancer, MCR - based methods should be able to distinguish diseased from healthy cells and then be used to selectively either destroy or modify the diseased cells.»
Protein - altering variants within 500 kb of 22 «index SNPs» uncovered in targeted sequencing of GWAS loci