Sentences with phrase «altering the level as»

It is amazing to progress through the game's dungeons and go over areas again and again with fresh challenges emerging and altering the level as you work through it.

Not exact matches

According to The Telegraph, Ohanian said: «Reddit offers the opportunity for us, as humans, to connect on a much deeper, broader level because users have an alter ego and aren't tied to a social network of friends with whom they want to share how perfect their lives are.»

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Massive demographic and economic shifts, as well as historic levels of technological and media disruption, are turning this once predictable industry — where «average» was king — into a sea of turbulent change, leaving consumer behavior permanently altered.

If altered levels of either hormone were to affect the appetite for financial risk, could this in turn destabilize the market as a whole?

The Court's own case law shows that in order to maintain the abortion right at the level of fundamental law, many other sectors of the states» legal order, at both statutory and common law, need to be altered: family law, marriage law, laws regulating the medical profession, and, as we now see with the recent circuit court decisions, criminal laws prohibiting private use of lethal force.

Here is a guest post from A. Vogel When doing a detox, it is common to experience a period of discomfort on some level, whether physically as the exit routes start to open up, or emotionally as the diet is altered and certain foods avoided or lifestyle changes implemented.

«For instance, we have developed flavor compounds that can effectively mask the off - notes that functional ingredients such as vitamins and minerals contribute to the flavor profile, or that can alter the perception of traits such as sweetness or cooling levels,» Callahan notes.

Enjoy features such as water level detection, adjustable brew safety light, and gravity hot - water faucet system that let you access hot water while brewing without altering brew volume.

Depression may affect maternal response via altered sensitivity to their infant's signal.34 Schuetze and Zeskind34 show that perception of infant crying varies with level of maternal depression: as the level of depression increases, infant crying is perceived as less urgent and sick - sounding (i.e., less aversive and less arousing).

Supplements of vitamin C for a mother do not significantly alter the amounts in breastmilk, as they remain fairly constant no matter what mother's intake levels (assuming the mother is not vitamin - C deficient).

The colours act as a reminder for you to cool or heat the room, to modify the baby's clothing, to use a different tog Grobag Baby Sleep Bag or for non-sleep bag users to alter the level of bedding.

Modifying the vegetation cover alters the surface properties — such as the amount of heat dissipated by water evaporation and the level of radiation reflected back into space — which has a knock - on effect on local surface temperature.

But unlike the normal mice, those with altered macrophages showed no signs of inflammation, such as changes in insulin production, high levels of immune chemicals, and macrophages in their belly fat.

By altering the exhaust level as the car runs, the cylinders supply themselves with just the right amount of fuel and air they need at any one time — as befits a pair of mechanical lungs.

As climate change alters weather patterns — hastening desertification in some places and sopping others — increases the strength of natural disasters — from cyclones to landslides — and raises sea levels world wide, it will make many areas and livelihoods untenable, say the authors.

Then although this rating can in principle be altered as a result of discussions by the study section, the level of modification which occurs in practice is quite minimal.

«When cells are stressed, for example when nutrient levels are low, they alter protein production as a survival strategy.

Altered sphingolipid levels in blood have been associated with depression and have been proposed as a therapeutic target for major depressive disorder.

Certainly, miRNA levels do not remain altered in the brain cells of mice injected with sperm miRNAs as zygotes.

We may also need to accept altered coral reefs in the future, as different types of coral show differing levels of resilience.

A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and process information at a systems level in order to alter cell behavior.

The researchers also discovered that other stresses, such as altering salt levels in the shrimp tanks, cause them to become cloudy as well.

Researchers at the Childhood Obesity Research Center at USC are looking at how maternal food intake affects fructose levels in breast milk as well as how specific elements in breast milk can alter a baby's developing gut bacteria, which neutralizes toxic byproducts of digestion.

Yet in addition to extinctions there are many dramatic, well - documented effects of introduced species, such as shifts in regional climate, reduced groundwater levels, altered nutrient cycling, and reduced oxygen levels in aquatic systems, which affect the abundance and distribution of native species.

«It was surprising to see all these significant changes in A1C and body weight without altering medications or activity level and without aiming for weight reduction,» Dr. Hamdy pointed out, «Which tells us that nutrition therapy can be as effective as medications even after a long duration of the disease.»

Research such as Alter et al.'s work points to the importance of becoming increasingly more specific about the situations and conditions that engage these distinct systems, which will prove to be essential in understanding how these multiple systems interact at a neural level.

When the coupling laser came back on, the incoming jolt of energy caused the altered sodium atoms to shift energy levels, in the process releasing a light pulse of the exact phase and amplitude as the one originally sent in by the probe laser.

They were able to identify altered levels of a molecule (also called microRNA) in individuals as much as twenty years before the expected onset of symptoms.

Prozac and its ilk quickly alter levels of chemicals such as serotonin in the brain, but they typically take weeks to ease depression symptoms.

In addition, the altered rates of force development and relaxation suggest alterations in the regulation of intracellular calcium levels following maximal contractions, as are noted to occur in slow skeletal muscles (44).

Furthermore, samples that have been genetically manipulated to alter the target's levels (e.g., CRISPR) can be used as a negative control.

These studies are unable to determine a causal relationship due to factors such as gene regulation — a genetic variant may instead contribute to altered expression levels of true causal genes, which remain undetected by a GWAS.

A study of the transcriptome of this whale's organs showed that it has better insulin and whole - body glucose disposal (this alters longevity through the IGF - 1 axis) as such its pancreatic Beta cells secrete enough dosed insulin to reduce fasting and post-prandial blood glucose levels.

Modern aquatic ecosystems are infiltrated with diverse mixtures of pollutants that can act together as a multiple stressor to alter biotic systems at all levels of biological organization, including individuals, populations and communities.

As previously reported, the expression level of dilp3 is very low during the growth period (S3A Fig)[13][14], and neither growth nor developmental timing is altered in dilp3 - null mutants [25].

However, while heme has been reported to induce nuclear export and subsequent cytoplasmic degradation of Bach1, HPP - 4382 does not appear to alter the steady - state levels or nuclear - cytoplasmic distribution of Bach1 (data not shown), suggesting that HPP - 4382 may not fully mimic the action of heme as a ligand of Bach1.

These findings raise the question as to how reduced 5 - HT and TPH2 levels are related to the increased 5 - HT cell density, 11 morphologic 5 - HT neuronal immaturity, 11 reduced 5 - HT transporter binding relative to 5 - HT cell number, 11 and altered 5 - HT receptor binding9 - 11 in the SIDS cases.

The results indicate that, if CERs are accepted as eligible units of compliance under CORSIA without any restrictions, the demand for offset credits from international aviation to 2035 is unlikely to either materially impact the current price level for CERs or alter the overall level of greenhouse gas abatement undertaken.

There may be a certain level of complexity in elucidating the mechanisms involved in this negative response as we have shown that the response can be easily altered with expression of either ER - α or N1 - ICD, and this suggests that the intrinsic hypoxic response of these cells can be overcome quite simply.

Battles for the soul have been fought while either tapering steadily off the mind - altering medications and working consciously with the debilitating withdrawal symptoms, or without the added burden of the medications, simply working to bring balance on a deeper soul level in order to engage more fully in life as a balanced and constructively engaging human being.

«The available research, such as there is,» she says, suggests that «progesterone can alter the body's fuel metabolism and its ability to handle heat,» she says, meaning that women will probably feel hotter and more fatigued during prolonged exercise in the second half of their menstrual cycles, when progesterone levels rise, than before menses, when progesterone is low.

A study found that children with autism have altered gut flora «working as neurotransmitters or controlling neurotransmitter biosynthesis» and researchers «suspect that gut microbes may alter levels of neurotransmitter - related metabolites affecting gut - to - brain communication and / or altering brain function.»

I would be shocked to see somebody with hair loss that had a healthy scalp pH so adding (quality) lactobacillus probiotics to your diet along with healing a leaky gut (many resources on the internet tell you how to do that) will not only alter skin pH to a healthy level but stop the chronic inflammation which, as is so rightly mentioned in this article, the catalyst for every disease / condition which we develop.

When women's estrogen levels decrease during menopause, blood vessels can become rigid and less responsive to changes in blood flow and blood flow - altering mediators such as nitric oxide.

Intakes of 150 — 450 mg of zinc per day have been associated with such chronic effects as low copper status, altered iron function, reduced immune function, and reduced levels of high - density lipoproteins [82].

Exposure to high levels of infectious microbes, environmental chemicals such as plasticizers, pesticides, herbicides, personal care products, heavy metals and biotoxins such as mold wear down the bodies glutathione levels, alter the gut microflora and increase inflammatory activity in the body.

Environmental Toxins: Exposure to high levels of infectious microbes, environmental chemicals such as plasticizers, pesticides, herbicides, personal care products, heavy metals and biotoxins such as mold wear down the bodies glutathione levels, alter the gut microflora and increase inflammatory activity in the body (26, 27, 28).

As you progress, exercises must be altered to match the growth or decline of your energy levels and physical abilities.

Altered cortisol levels increase the risk for developing chronic conditions, such as autoimmune disease, chronic pain, or chronic inflammation.