«There is no doubt that mefloquine does cause more sleeplessness, abnormal dreams, anxiety and depressed mood than the
alternatives» says Dr Tickell - Painter, «but the review clarifies that these are symptoms reported by people taking mefloquine and not formal
psychiatric diagnoses.
Subjects also completed the 30 item version of the general health questionnaire.17 The Karnofsky performance index was scored at follow up by one of us (AW) after an interview with each subject.18 This interview was also used to evaluate the possibility of
alternative medical or
psychiatric diagnoses, 11 with the benefit of details of longitudinal course.