Third, chronic stress associated with family violence may
alter hypothalamic - pituitary axis functioning, lead to dysregulation of neuroendocrine systems controlling
appetite, and influence hormonal
regulation of visceral fat distribution.35 Other traumatic childhood experiences have been linked to
altered serotonin and cortisol systems.70 Overlapping research has shown that bulimia is associated with decreased serotonin metabolites in cerebrospinal fluid,71 - 73 reduced platelet binding of serotonin reuptake inhibitors, 73 reduced density of paroxetine - binding sites, and
altered cortisol function.70 Thus, early - life disruption of neuroendocrine systems may elevate risk for disordered eating behaviors and suboptimal fat storage and distribution.