Sentences with phrase «although mouse studies»

Remarkably, although mouse studies had indicated that different transcription factors were differently important for generating pain and itch sensing neurons versus pressure and limb position neurons, in the dish these factors produced equal numbers of each of the three main subtypes.

Not exact matches

A recent study in mice found just a single session of exercise before catching flu reduced disease severity, although regular exercise beforehand worked even better.

Although some of the mice subsequently gave birth, more studies will be needed to confirm the results.

Although the study was conducted in a mouse model, the outcomes may be applicable to humans,» explains Dr. Jiang.

But recent studies in both humans and lab mice have suggested that motor neurons in the brain — the upper motor neurons — may be involved in disease progression, although the extent and significance of this involvement has remained unknown.

Although IL - 37 was identified 15 years ago, studying its function has proven difficult as it is not synthesised in mice.

Insects are an important model for the study of emotion; although mice are closer to humans on the evolutionary family tree, the fruit fly has a much simpler neurological system that is easier to study.

Studies in mice specially bred to have features of the disease found that DHA reduces beta - amyloid plaques, abnormal protein deposits in the brain that are a hallmark of Alzheimer's, although a clinical trial of DHA showed no impact on people with mild to moderate Alzheimer's disease.

«The protection from recurrent diabetes in the mice was not permanent, although some studies would suggest that processes in mice are highly accelerated, so four months in mice might translate to several years in humans,» Gittes says.

Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging - independent, mechanisms.»

Although the effect of sleep deprivation was stark in this study, Rolls and her colleagues found that it could be reversed by letting the drowsy mice catch up on their ZZZs.

Verma is quick to point out that although there have been two case studies in which BRCA1 mutations were linked to brain abnormalities, the dramatic effects documented in the mice in the study are unlikely to occur in women with a BRCA1 mutation, who still have some functioning BRCA1, compared with the mice who had none at all.

Although it isn't possible to make true mouse models of schizophrenia, the study is «elegant» and an «important new building block» toward a better understanding of the MD's role in schizophrenia's cognitive deficits, says psychiatrist John Krystal of Yale University.

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center San Antonio found.

Although very promising, the study was done in vitro and in mouse models so more research is needed to prove it is safe and effective before it can be tested in the clinic.

Although the omega - 3 diet did not improve cognitive outcomes in the mice, the researchers expect their model will be useful for studying alternative lifestyle interventions to ameliorate the chemobrain phenomenon.

Although the metabolic effects of osteocalcin are still being elucidated (58, 59), several studies suggest that undercarboxylated osteocalcin regulates glycemic control and lipid metabolism in mouse models (27, 30, 60).

Similarly, although the mice were obtained from the same source, housing the animals in a different facility may have contributed to differences between the studies.

Previous studies have reported an increase in fatigue resistance in EDL muscles following genetic manipulation of Actn3 (40) and Pgc - 1α (41), although differing fatigue protocols preclude direct comparison with the current data in the IL - 15Rα — KO mouse.

Although mouse models of Huntington's exist, it is difficult for researchers to study certain aspects of the disease.

The current study reports neurogenesis (neuron creation) occurred in the spinal cords of both adult and aged (over one - year old) mice of both sexes, although the response was much weaker in the aged mice, Dr. Zhang said.

EEG studies demonstrated that although C57BR / cd mice spend less time sleeping, a greater proportion of their sleep time is spent in paradoxical sleep (PS)(equivalent to human rapid eye movement, or REM sleep) than is true of mice of six other inbred strains tested (Pagel et al. 1973).

Although the Badovinac study does mention that immunization of B6 Prf1 − / − mice followed by LCMV infection results in mortality with LCMV - specific CD8 T cell expansion (as do naive B6 Prf1 − / − mice), these data were not shown as the focus of the report was on the BALB / c model.

Although this study was done in mice, the same mechanisms were found in human macrophages infected with TB.

Although progress toward harnessing the immune system to attack tumors has been «enormous,» he said, his lab and many others are seeing in more and more studies — in lab mice as well as patients — that «immuno - oncology» will not be as simple as stimulating T cells to attack tumors.

Although vaccination induces an inflammatory response during pregnancy, the magnitude and the duration of response is much lower and shorter, respectively, for influenza vaccination than viral infection.27 Like infection, influenza vaccination during pregnancy has been reported to induce a transient increase in the levels of a number of proinflammatory cytokines, including interleukin 6, tumor necrosis factor α, and C - reactive protein.27 - 30 Studies on mice found an association between high interleukin - 6 levels during pregnancy and abnormal behavior and brain structure.19 However, in epidemiological studies, associations between maternal cytokine levels and ASD have beenStudies on mice found an association between high interleukin - 6 levels during pregnancy and abnormal behavior and brain structure.19 However, in epidemiological studies, associations between maternal cytokine levels and ASD have beenstudies, associations between maternal cytokine levels and ASD have been mixed.

Although resurgence did not occur in as many tissues of antibiotic - treated mice as the first experiment, results of this repeat study confirmed resurgence of non-cultivable B. burgdorferi at 12 months following treatment.

However, the second form of immune selection — passage of acute - phase parasites from hosts injected with antiserum at the beginning of the infection — yielded parasites with lower virulence to naïve mice than their ancestors in one study (Wellde and Diggs 1978), although it had no impact on virulence in two other studies (see Briggs and Wellde 1969).

Although red therapy light helps to modulate the immune system, a 2006 study with mice found that over treatment actually resulted in immune suppression.

bergamia essential oil's calming properties can be as strong as diazepam (valium)[5], although it's important to note that in this animal study, mice received injections of bergamot C. aurantium var.

Although there are several studies demonstrating the benefits of keto diets for people with NAFLD, concerns have also been raised in light of several studies reporting that long - term ketogenic diets actually promote the development of fatty liver disease and oxidative stress in mice (33).

«Although more clinical studies need to be done, it appears possible that similar to mice, patients would have improved insulin sensitivity with omega - 3 fatty acids, with no increased risk of heart disease,» Smith told MyHealthNewsDaily.

Although studied on mice, the response was clear and the researchers concluded that diapers should be considered as one of the factors that might cause or exacerbate asthmatic conditions.4

3) Although no mice were tested on to write this book, with the help of mouse studies, scientists have identified many genes that play roles in addiction.