«This study sheds new light on how unique combinations of proteins, as opposed to single protein sources, are important for muscle recovery following exercise and help
extend amino acid availability, further promoting muscle growth,» said Blake B. Rasmussen, chairman of UTMB's Department of Nutrition and Metabolism and lead researcher of the study.
The double - blind, randomized clinical trial included 16 healthy subjects, ages 19 to 30, to assess if consumption of a blend of proteins with different digestion rates would
prolong amino acid availability and lead to increases in muscle protein synthesis after exercise.
TOR plays many roles, but one of its primary tasks is to function like a wrench loosening and tightening the control of protein synthesis in response to nutrients,
specifically amino acid availability.
Other anti-nutrient factors inherent to lentils are trypsin inhibitor (TI), which inhibits proteolytic activity of the digestive enzyme trypsin and hence
reduces amino acid availability, and condensed tannins, which cross-link with vitamins, minerals, carbohydrates, and protein, and specifically render lysine or methionine unavailable (Vidal - Valverde et al., 1994).
One enzyme, RagA, has been found to regulate the mechanistic target of rapamycin complex 1 (mTORC1) pathway in cells according to glucose and
amino acid availability.