Sentences with phrase «amino acid sequences»

Predicting amino acid sequences and epidemiology link to 2.1.3 6.

*** Students have to complete a challenging cut and stick activity to consider impacts of base deletions, additions and substitutions, on the base and amino acid sequences.

This occurs in the lamina propria and crypt regions of the intestine when the patient eats specific food - grain antigens, or toxic amino acid sequences.

The ultimate goal here is to figure out if the amino acid sequences that are toxic to people with Celiac are still present in the beer.

A predicted amino acid sequences (Version 3) of pisifera p5 - build that had similarity to known genes in RefSeq with oil palm transcriptome evidences.

Instead, biologists may have to understand and control variations, or codes, of amino acid sequences in the protein that apparently guide them to engage in certain kinds of assemblies and prevent droplet assemblies from turning into tangled knots.

The Bioinformatics group uses computational methods to analyse genome sequences, amino acid sequences, and gene expression data, both to identify new genes of interest and to determine their structure, function and role in the cell.

In the lab Fawzi is now studying how altering amino acid sequences affects FUS behaviors in hopes that it will lead to a clinically useful strategy against ALS and cancer.

The classic data of bioinformatics include DNA sequences of genes or full genomes; amino acid sequences of proteins; and three - dimensional structures of proteins, nucleic acids and protein — nucleic acid complexes.

For example, it is used to identify correlations between gene sequences and diseases, to predict protein structures from amino acid sequences, to aid in the design of novel drugs, and to tailor treatments to individual patients based on their DNA sequences (pharmacogenomics).

(B) Deletions in CCHa2 mutant alleles and the resulting amino acid sequences.

An engineer designing a protein that has 1000 amino acids may choose among some 101300 different amino acid sequences.

[8 - 11] In the AFFITOME system, antibodies specific to the physiological target are used to screen peptides whose amino acid sequences are unrelated to the original target antigen (and also, ideally, to other physiological antigens).

The amino acid sequences of the Plasmodium interspersed repeat (pir) genes were extracted from five genomes (PcyM, P. vivax P01, P. coatneyi, P. ovale curtisi and P. knowlesi).

Molecular mimicry is the tendency of the immune system to cross-react from a primary target antigen to other, unrelated peptides («neo-epitopes») with distinct amino acid sequences and / or similar conformational structures.

Masses of the resulting fragments are measured, and computer algorithms match the results with known or predicted molecules whose amino acid sequences are either known or inferred.

Thrombin also propagates coagulation by activating various proteins by proteolysis — cleaving them at specific points in their amino acid sequences.

Modern molecular technologies (genomics and other omics), through comparing nucleic acid and amino acid sequences across living species, are enabling the identification of genetic components and patterns stingily conserved by evolution, from those in which times of evolutionary branching of the tree of life can be inferred.

It is already possible to predict with surprising accuracy the folds of many simple monomeric proteins directly from their amino acid sequences — no experimental structure determination required.

However, thanks to subtle differences in their amino acid sequences, the more stable myoglobins are better able to retain their shapes.

Although this intriguing possibility remains theoretical, the similarities in the amino acid sequences of NGF and insulin are not great enough to result in any similarity of function: the two molecules have completely different target cells and biological activities.

Analysis of the DNA and encoded amino acid sequences of A14 and B9 revealed that the first two are clonal variants which aligned most closely to the germ line denoted VHH Vg (T Verrips, unpublished data) and that the sequence of B21 is highly divergent from both and also aligns to a different germ line V gene sequence Vu.

The DH31R and Calcr proteins have a common biological ancestry and similar amino acid sequences.

Collins already had developed a method to identify ancient species by differences in the amino acid sequences of collagen and other proteins preserved in fossils.

Researchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of the protein, which have nearly identical amino acid sequences, exhibit distinct three - dimensional structures at the atomic level.

«For dog - related rabies, host jumping was linked to multiple evolutionary patterns, such as parallel changes in amino acid sequences between different host species, suggesting that dog - related rabies may not need to evolve much to jump to new carnivore hosts.»

For dog - related rabies, host jumping was linked to multiple evolutionary patterns, such as parallel changes in amino acid sequences between different host species.

Applying a technique known as mRNA display, the fragments are tagged in specific way, such that amino acid sequences resulting from successful translation events remain bound to the mRNA fragments that generated them.

Graur compared amino acid sequences in 91 proteins from humans, monkeys, rats, rabbits, and other mammals.

That's because its surface protein haemagglutinin doesn't contain many short amino acid sequences — called epitopes — that trigger helper T - cells in the body to stimulate antibody - making cells.

UCLA researchers have created a code to translate amino acid sequences into music, to inform and entertain non-scientists and children.

The proteins that bacteria secrete are labeled with unique amino acid sequences, which tell the cells that the proteins are destined for secretion.

The deduced amino acid sequences indicate an evolutionarily highly conserved protein that spans the membrane four times.

Although the samples contained little protein, he was able to reconstruct the amino acid sequences of seven collagen fragments.

To provide a molecular basis for understanding N - CAM function, the complete amino acid sequences of the three major polypeptides of N - CAM and most of the noncoding sequences of their messenger RNA's were determined from the analysis of complementary DNA clones and were verified by amino acid sequences of selected CNBr fragments and proteolytic fragments.

Their method depends on encoding pairs of protein amino acid sequences with the information needed to direct molecular assembly through protein - protein interfaces.

The program was originally created to predict natural protein structures from amino acid sequences.

Most orthology determination methods make use of sequence comparisons: the amino acid sequences of all proteins in two species are compared with each other, and the two sequences that are most similar are considered to be orthologs.

Finally, they analyzed those same regions with Harvard University mass spectrometry specialist John Asara, who got the weights of six collagen fragments, and so worked out their amino acid sequences.

Critics also noted that one of the six amino acid sequences reported in the 2007 paper was misassigned and is likely incorrect.

They found that the proteins of prokaryotes (the group of organisms that includes bacteria and blue - green algae) tended to have sequences of about 150 amino acids, or a multiple of that number, while the proteins of the eukaryotes (which account for all other organisms) had amino acid sequences in multiples of around 125.

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells.

«It was not a truly modular code,» Boyden says, referring to the protein's amino acid sequences.

The tools included TCRdist, which researchers used to calculate the similarity and differences of key features of T cell receptors, such as amino acid sequences in important regions for antigen recognition.

«We were looking at the amino acid sequences of T cell receptors when Tomer asked what the corresponding epitope was for a particular receptor,» Thomas said.

They use this peptide «skeleton» to generate thousands (or even hundreds of thousands) of possible amino acid sequences that could support stable interactions for that conformation.

There is no such «direct» evolution: animals, bacteria, and algae have a common ancestor from which they have diverged, as can be shown by aligning and comparing amino acid sequences of proteins and nucleotide sequences of homologous ribosomal RNA molecules that are found in both bacteria and vertebrates.

I love biology, every pain staking detail of DNA - one mess up in an amino acid sequence and you get sickle - cell anima, or the proteins don't function correctly.

A mutation in DNA could cause a change in the amino acid sequence in a polypeptide.

The open reading frame of the sequenced clone coded for 97 amino acids, including the known amino acid sequence of this polypeptide.