Sentences with phrase «amount of rate change»

Not exact matches

For Business Insurance and Bond & Specialty Insurance, retention is the amount of premium available for renewal that was retained, excluding rate and exposure changes.

Expenses can be divided into fixed (those that must be paid, usually at the same rate, regardless of the volume of business) and variable or semivariable (those which change according to the amount of business).

This would mean significant change to the amount of greenhouse gas in the atmosphere and would slow down the rate of warming.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The market expected that Britain would have to devalue its currency and no amount of interest rate hikes or currency purchasing would change that.

The market expected that Britain would have to devalue its currency and that no amount of interest rate hikes or currency purchasing would change that.

Duration is a measure that helps estimate the amount the price of a bond will rise or fall in response to changes in interest rates.

Forward - looking statements may include, among others, statements concerning our projected adjusted income (loss) from operations outlook for 2018, on both a consolidated and segment basis; projected total revenue growth and global medical customer growth, each over year end 2017; projected growth beyond 2018; projected medical care and operating expense ratios and medical cost trends; our projected consolidated adjusted tax rate; future financial or operating performance, including our ability to deliver personalized and innovative solutions for our customers and clients; future growth, business strategy, strategic or operational initiatives; economic, regulatory or competitive environments, particularly with respect to the pace and extent of change in these areas; financing or capital deployment plans and amounts available for future deployment; our prospects for growth in the coming years; the proposed merger (the «Merger») with Express Scripts Holding Company («Express Scripts») and other statements regarding Cigna's future beliefs, expectations, plans, intentions, financial condition or performance.

Rainfall, both the amount and the rate, represents one of the strongest signals of climate change.

Your payment amount can change depending on HELOC interest rate fluctuations, your credit line balance and the number of days in each month.

Factors that could cause actual results to differ materially from those expressed or implied in any forward - looking statements include, but are not limited to: changes in consumer discretionary spending; our eCommerce platform not producing the anticipated benefits within the expected time - frame or at all; the streamlining of the Company's vendor base and execution of the Company's new merchandising strategy not producing the anticipated benefits within the expected time - frame or at all; the amount that we invest in strategic transactions and the timing and success of those investments; the integration of strategic acquisitions being more difficult, time - consuming, or costly than expected; inventory turn; changes in the competitive market and competition amongst retailers; changes in consumer demand or shopping patterns and our ability to identify new trends and have the right trending products in our stores and on our website; changes in existing tax, labor and other laws and regulations, including those changing tax rates and imposing new taxes and surcharges; limitations on the availability of attractive retail store sites; omni - channel growth; unauthorized disclosure of sensitive or confidential customer information; risks relating to our private brand offerings and new retail concepts; disruptions with our eCommerce platform, including issues caused by high volumes of users or transactions, or our information systems; factors affecting our vendors, including supply chain and currency risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and risks associated with being a controlled company.

Due to the large and expanding scale of our international business activities, any changes in the U.S. or foreign taxation of such activities may increase our worldwide effective tax rate and the amount of taxes we pay and seriously harm our business.

However, if the ordinary shares or ADSs are treated as traded on an «established securities market» and you are either a cash basis taxpayer or an accrual basis taxpayer that has made a special election (which must be applied consistently from year to year and can not be changed without the consent of the IRS), you will determine the U.S. dollar value of the amount realized in a non U.S. dollar currency by translating the amount received at the spot rate of exchange on the settlement date of the sale.

That change would have raised revenue to help Republicans offset the losses from the massive rate cuts, and some proponents of it argued that the state and local tax deduction (known as «SALT») amounted to a federal subsidy of high - tax states.

When interest rates change, a bond's price will change in the opposite direction of rates by a corresponding amount.

The amount of return you receive on an exchange traded note depends on and is based on the performance of a specific market index; whereas, the value of the exchange traded note is affected by changes in credit ratings...

However, in most cases the amortization period changes because different borrowing terms, interest rates and payments against the principal amount at each renewal vary the length of time required to pay off the mortgage.

Monetary policy is maintained through actions such as modifying the interest rate, buying or selling government bonds, and changing the amount of money banks are required to keep in the vault (bank reserves).

The velocity of money measures the rate at which money flows through an economy, in other words, how much money changes hands; it has to do with the amount of economic activity associated with a given money supply.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

I recommend a major change to the tax system: Replace the intrusive loophole - ridden income tax with the combination of a universal fixed - rate sales tax and a universal fixed - amount rebate.

Mortgage calculators are automated tools accessible over the internet and help determine the effect of changes to any of the mortgage loan components such as the interest rate, repayment amount, principal amount, etc..

Dana has intimate familiarity with what it takes to make significant changes in a large, urban district like my own, and she is less - than - starry - eyed about the ability of any other district to follow suit without outside funding — over and above the current USDA reimbursement rate, OR that amount plus six cents.

Some Democratic lawmakers have raised the possibility of making some changes to the cap law, which limits increases in the amount collected in taxes to 2 percent or the rate of inflation.

They found that after 180 days neither dose led to measurable changes in the soil's mix of DNA and molecules found in bacterial cell walls (which reveals the amount and types of bacteria present), its levels of nutrients or rate of CO2 formation — the latter of which reflects how well the bacteria are utilizing oxygen.

In fact, changes due to mutations in the mitochondrial DNA over time can be used to distinguish groups and also to estimate the amount of time that has passed since two individuals shared a common ancestor, as these mutations occur at predictable rates.

Paleontologists have long suspected that these observations reflect a fundamental coupling between the rates of species formation and anatomical change: groups of organisms that contain lots of species also seem to have greater amounts of anatomical variation, while groups with only a few species, such as the gar, lack much morphological variety.

Any massive, long - term changes in their numbers could alter fish migration patterns, growth rates, and mortality, as well as change the amount of oxygen and carbon dioxide in the atmosphere.

«The amount and diversity of pesticides, pharmaceuticals and other industrial chemicals that humans are releasing into the environment are increasing at rates that match or exceed recent increases in CO2 emissions, nutrient pollution from nitrogen fertilizers, and other drivers of global change,» Bernhardt said.

This distribution remained the same when they changed the rate and amount of shaking, the density of the particles and the shape of the container.

To quantify the overall effect of contrast - dependent changes to output nonlinearities, we constructed a measure of how these adaptive shifts change the amount of information a unit's firing rate carries about the ongoing stimulus (Figure 5F).

Rate of change question — would methane - using microorganisms be likely to have handled most methane as it was released from warming at geological rates of change, but not increase fast enough to metabolize the amounts of methane described at current rate of chaRate of change question — would methane - using microorganisms be likely to have handled most methane as it was released from warming at geological rates of change, but not increase fast enough to metabolize the amounts of methane described at current rate of charate of change?

Studies have shown that even when people have lost huge amounts of weight, the actual change in their basal metabolic rate is around ~ 10 % -15 %.

In the short term, your body will undergo the following changes: ventilation (respiratory rate) increases in response to a lower amount of oxygen in the blood, blood then becomes more alkaline (meaning less acidic) as you hyperventilate, and this alkaline state in turn signals your body to breathe less than you should in order to get substantial oxygen to your tissues.

In animal studies, changes include decreased body temperature, less spontaneous activity, and lowered resting metabolic rate (the amount of energy the body uses while at rest.)

Also the fiber in the nuts changes the rate that the fats in the nuts is absorbed, so that would change the amount of fat in the blood, since the body is also working to remove the fat and put it into storage.

Even if the caffeine was capable of raising your metabolic rate by 100 calories in a day, this amount wouldn't change the amount of body fat you have.

You're just static in that chair, and so watching these images on the screen are potentially changing your heart rate, your blood pressure, the amount of stress hormone that's floating through your blood stream in that moment, and maybe those images that you see in the movie have such staying power that you have a nightmare that night or you can't sleep very well.

So, for an overwhelming amount of people (really, everyone Dr. Maffetone has looked at) the MAF heart rate does not change with sport.

When your thyroid doesn't produce the correct amount of hormone, you may experience changes in heart rate and other concerning symptoms.

The Chinese no longer eat this way today, opting instead for increasing amounts of meat; their decreasing health and rising obesity rate is a reflection of this recent change.

Until now we were recalculating the amount in your currency on the date of the actual member payment and on the date when the payment is made to you therefore the amounts may have changed quite noticeably when the rate rose or dropped significantly.

Because of changing military assignments, the maximum amount of time most children spend in one school is three years; the annual mobility rate is 35 percent.

Beginning in 2003, after our data were collected, the Chilean government sought to alter several features of the system, although not all of the changes have been fully implemented: Rather than providing vouchers at a flat rate, voucher amounts are to be tied to family income.

Comparing changes in search rates to mobility rates also provides a lower bound on the amount of online searching done by existing residents because of choice.

I say «might be» because, in modelling this situation, one can not get away from the dependence on multiple factors, such as the 5 listed above So if (for example) the natural rates of deceleration after downshifting and in neutral are the same, that doesn't mean it would take the same force of stepping on the brakes in both cases to further change the deceleration by the required amount.

The cooling rate of the evaporator has not changed, it is still pulling in a fixed amount of heat.

«When the driver selects a new mode, the software will enable some new subsystems, disable others, and reference new columns and rows in calibration tables, which change the amount of torque, rate at which torque is increased or decreased, and how the torque is biased left and right,» Kuczera said.

However, rather than change the balance of the car, the spring rates increase by the same amount front and rear to maintain some consistency in the way the Cayenne drives.

Being able to change the spring rate (the system reduced the amount of air when it needs to increase the spring rate — less air is harder to compress for a given suspension movement) in conjunction with tuning the damping rate via Porsche's PASM (Porsche Active Suspension Management) system is key to the Panamera's ability to offer excellent ride and yet still deliver sharp, sports - car - like handling.