Sentences with phrase «amounts of cell signaling»

The researchers found that, in response to the maximum tolerated doses of several commonly used chemotherapy drugs, breast cancer - associated fibroblasts secrete large amounts of cell signaling proteins called ELR + chemokines.

Not exact matches

«The problem with plasma cell - free liquid biopsy in particular is that the amount of wild - type [DNA] can be very, very high, and so keeping that really rare signal from being swamped out by the wild - type... is key,» says Dawne Shelton, R&D manager for in vitro diagnostic products at Bio-Rad in Hercules, California.

The group then ran dozens of microscopy tests with Dan Wagner, Rice associate professor of biochemistry and cell biology, to see how different formulations and amounts of biochar affected cell signaling.

«There's a large amount of validation to ensure specificity of the antibodies and to make sure that the antibody is actually recognizing the intended target,» says Craig M. Thompson, director of production and molecular assays, with Cell Signaling Technology (CST), located in Danvers, Massachusetts.

They depleted their reserves of these chemicals rapidly each time a new auditory signal came in, and they decreased the amount of space within the cells that housed sac - like structures called vesicles — biological storage tanks where neurotransmitter chemicals are kept.

The researchers also looked at the gene expression of skin cells from people with psoriasis and found decreased expression of the genes involved in pigmentation signaling, correlated with increased amounts of IL - 17 and TNF.

The study focused on the serotonin transporter, a molecule that regulates the amount of serotonin signaling between brain cells and is a major target for treatment of depression and mood disorders.

Neural signals are transmitted within neurons by changing calcium concentrations, so the researchers used this technique to measure the amount of calcium contained within the Purkinje cells in real time.

The new study revealed that pancreatic cancer cells not only send signals that make macrophages produce abnormal amounts of dectin - 1 surface receptors, but also that make tumor cells themselves express high levels of galectin - 9.

Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process of repairing myofiber.

Moreover, these stem cell - derived cells released different amounts of hormone in response to known feedback signals generated by other organs in the body.

This work builds on previous studies identifying the stem cell population in the nail bed by unveiling a signaling mechanism that could be exploited to enhance the amount of tissue that could be regrown.

Disrupted Stress Hormone Signals in Bone Cells Protect from Diet - Induced Obesity April 4, 2017 A high - calorie diet, even without a high amount of fat, causes bone loss, and both high - calorie and high - fat diets induce excessive fat gain and insulin resistance...

Such cells become dysfunctional exporters of harmful signals and oxidized proteins, something that contributes to the progression of atherosclerosis via increased amounts of oxidized lipids in the bloodstream, to pick one example.

In cells arrested overnight by a specific arrest signal, gene expression changes are largely signal - specific with a small amount of overlap.

Leptin signals your cells to release fatty acids to be burned for fuel and if your cells are ignoring it (i.e. resistant), your weight loss won't be proportionate to the amount of work you put into it.

This signals your pancreas to produce a large amount of insulin to get the sugar out of your blood and into your cells.

As a result, the cell nucleus doesn't hear the signal and doesn't call your pancreas to secrete the appropriate amount of insulin needed.

While some amount of omega - 6 s are important for membrane structure and cell signalling pathways (Institute of Medicine 2005), consuming too much can interfere with neurological development through inhibition of omega - 3 PUFA metabolism and availability (Novak et al. 2008).