Sentences with phrase «amplifying pain signals»

As King explains it, this channel is the first step in the process of amplifying pain signals up the spinal cord to the brain.

Chronic pain may be due to an overabundance of a protein, which amplifies the pain signal to the brain.

But when the immune system becomes activated in response to an illness or injury, glia in regions associated with pain processing seem to take on another role: They release inflammatory molecules that interact with nearby neurons to amplify pain signals.

Animal studies have revealed several ways in which opioids may amplify pain signals in the central nervous system, suggesting targets for drugs that could counter the effect.

In effect, this sodium channel amplifies the pain signal so it can be «heard» by the brain, says King.

Not exact matches

Researchers already knew that even without opioids, some people with chronic pain from nerve damage or fibromyalgia, for example, experience hyperalgesia when normal pain signaling gets reinforced and amplified over time.

They release more and more neurotoxic chemicals, and those, in turn, excite neurons, creating a feedback loop: overstimulated glia cause more and more inflammation, which activates stronger pain signals from neurons and amplifies pain.