Sentences with phrase «amygdala subregions»
A schematic of (a) the amygdala subregions in coronal view that we hypothesize are anchors for (b) three large - scale networks subserving processes important for social cognition.
http://www.jneurosci.org/
Hypothetical topographic model of amygdala subregions and their affiliated large - scale networks subserving social cognition.
Not exact matches
The lab has generated «floxed» alleles of GABAA receptor subunit genes that allow us to ablate the respective subunit in a subregion specific manner — e.g., in hippocampal subregions or the amygdala — either via a cross with cre - transgenic mice or via stereotaxic injection of cre - expressing viruses into defined brain regions.
A functional connectivity approach at the subregional level may therefore yield novel insights into GAD.To determine whether distinct connectivity patterns can be reliably identified for the basolateral (BLA) and centromedial (CMA) subregions of the human amygdala, and to examine subregional connectivity patterns and potential compensatory amygdalar connectivity in GAD.Cross - sectional study.Academic medical center.Two cohorts of healthy control subjects (consisting of 17 and 31 subjects) and 16 patients with GAD.Functional connectivity with cytoarchitectonically determined BLA and CMA regions of interest, measured during functional magnetic resonance imaging performed while subjects were resting quietly in the scanner.
The amygdala is composed of distinct subregions that interact with dissociable brain networks, which have been studied only in experimental animals.
Across the subregions, GAD patients had increased connectivity with a previously characterized frontoparietal executive control network and decreased connectivity with an insula - and cingulate - based salience network.Our findings provide new insights into the functional neuroanatomy of the human amygdala and converge with connectivity studies in experimental animals.
Based on our synthesis of published anatomical and functional data in humans and nonhuman animals (see Materials and Methods), we hypothesized that the amygdala would parse into three subregions that each anchor a large - scale network of brain regions implicated in distinct processes of social cognition.