She recently correlated
amygdala volume with the size of a person's social network.
Not exact matches
The areas where this
volume increase were seen include the hypothalamus (which is associated
with maternal motivation), the prefrontal cortex (which is associated
with judgment and reasoning), and the
amygdala (which is associated
with emotional processing).
The researchers found that in patients
with SAD, brain
volume and activity in the
amygdala decrease as a result of ICBT.
A larger network of Facebook friends correlates
with a greater
volume of gray matter in the
amygdala, an emotion - processing region, according to a recent study.
Compared to controls, patients
with schizophrenia demonstrated smaller bilateral hippocampus,
amygdala, thalamus and accumbens
volumes as well as intracranial
volume, but larger bilateral caudate, putamen, pallidum and lateral ventricle
volumes.
Specifically, individuals diagnosed
with major depression have smaller hippocampal and
amygdala volumes (34,35), structural and morphological changes in the prefrontal and orbitofrontal cortex (22), and basal ganglia structures (6).
In a separate group of healthy individuals, they used genotyping and neuroimaging to examine potential genetic associations
with amygdala volume in 1048 subjects and
amygdala function in a subset of more than 100 subjects.
Poverty was associated
with smaller white and cortical gray matter and hippocampal and
amygdala volumes.
Stress paradigms in rodent models have been associated
with elevated anxiety and contrasting alterations in neuronal morphology in the hippocampus and
amygdala,
with dendritic atrophy observed in the hippocampus and increased dendritic arborization in the
amygdala.12, 13 Developing rodents deprived of maternal nurturance show decreased hippocampal
volume and altered stress reactivity.14 An epigenetic mechanism for this effect has been elaborated.15 Importantly, controlled trials that have randomized institutionalized toddlers to early therapeutic foster care vs institutionalization have documented the deleterious effects of early relative deprivation on cognitive outcomes.16
We thank Michael I. Miller, PhD, and Tilak Ratnanather, PhD, of the Center for Imaging Science, Johns Hopkins University, for their technical assistance and insights
with the implementation of the large deformation diffeomorphic metric mapping to quantify the hippocampus and
amygdala volumes.
A recent fMRI study showed that the MAOA genotype at risk for impulsivity and violent behavior is associated
with reduced gray matter
volumes in limbic regions such as the
amygdala, dorsal anterior cingulated cortex (dACC), and subgenual ACC and greater
amygdala and subgenual ACC responsivity to negative emotional faces [25].
Preliminary evidence for persistent abnormalities in
amygdala volumes in adolescents and young adults
with bipolar disorder
Smaller
amygdala volumes have been found among youths
with disruptive behavior disorders which could also contribute to findings showing diminished reward sensitivity among these youths [84, 85, 86].
Magnetic resonance imaging of HPC and
amygdala volume in women
with childhood abuse and borderline personality disorder
A negative correlation between aggressiveness and local gray matter
volume in the left
amygdala has been reported for adolescents
with conduct disorder (Sterzer et al., 2007).