Amyloid angiopathy is a condition where a protein called amyloid builds up in the walls of blood vessels in the brain. This buildup can make the blood vessels weaker and more prone to bleeding or leaking, which can cause problems like strokes or brain hemorrhages.
Full definition
In addition, neurofibrillary tangles pathology was observed in apes that exhibited plaques and moderate or severe
cerebral amyloid angiopathy and in one individual with virtually no amyloid beta pathology.
While approximately 80 percent of Alzheimer's disease patients also have cerebral
amyloid angiopathy, or amyloid beta deposits in the brain's blood vessels that increase the risk for stroke and dementia, the predominant amyloid beta pathology is plaques.
The protein causes familial human cerebral
amyloid angiopathy (CAA), and the study, which appears in Nature Communications, is the first to examine forms of the protein in three different species.
Spatial distribution of white - matter hyperintensities in Alzheimer disease, cerebral
amyloid angiopathy, and healthy aging.
Abstract: Cerebral
amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly.
Keywords: Cerebral
amyloid angiopathy, neuroimaging markers, neuropsychological assessment, visuospatial functioning
Cerebral
amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly.
Dr. Mar Hernández - Guillamon has dedicated her career to the study of Aβ - associated pathologies, including AD and cerebral
amyloid angiopathy.
In particular, during the predoctoral and postdoctoral periods, I studied the molecular mechanisms involved in the neurovascular disorder known as cerebral
amyloid angiopathy (CAA).
There were no amyloid plaques in the frontal cortex and abundant Abeta - immunoreactive macrophages, but tangles and
amyloid angiopathy were present.
Affected family members presented between 61 and 74 years, with variable presence of microbleeds / cerebral
amyloid angiopathy and electroencephalographic abnormalities.
Keywords: Alzheimer's disease, amyloid - β, APP, calcification, cerebral
amyloid angiopathy, mutation
Abstract: Background: Specific APP mutations cause cerebral
amyloid angiopathy (CAA) with or without Alzheimer's disease (AD).
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