According to the authors, vascular damage may predispose your brain to increased
amyloid plaque buildup, which is a hallmark of this degenerative brain disease.
The study discovered that those who awoke more than 5 times every hour were more likely to have
amyloid plaque buildup when compared to those who didn't awaken that much.
The actual process of vascular aging may predispose a person's brain to the increased amount of
amyloid plaque buildup.
For example, Eli Lilly & Co. (NYSE: LLY) has a phase 3 study of solanezumab under way in mild to moderate Alzheimer's disease patients that may slow disease progression by breaking up
amyloid plaque buildups thought to be a major cause of the disease.
Not exact matches
The «
amyloid hypothesis» figures that a
buildup of brain
plaque is what leads to the cognitive decline that Alzheimer's patients experience.
The bulk of research scientists working on Alzheimer's have long believed that a
buildup of
amyloid «
plaques» is central to the disease's development — and that therefore targeting this protein is the best chance for a cure.
For one, it would give them three specific biological markers to hone in on: The
buildup of beta
amyloid and tau proteins, which cause brain
plaques associated with Alzheimer's, and brain nerve cell death.
Recent research also has illuminated how the deadly cascade that leads to brain atrophy is set in motion: The
buildup of
amyloid plaques, working in tandem with certain gene mutations, sparks the formation of the renegade tau proteins.
Like cardiovascular disease, Alzheimer's involves the
buildup of
plaque, in this case tangled beta -
amyloid proteins in the brain.
More than 40 illnesses known as
amyloid diseases — Alzheimer's, Parkinson's and rheumatoid arthritis are a few — are linked to the
buildup of proteins after they have transformed from their normally folded, biologically active forms to abnormally folded, grouped deposits called fibrils or
plaques.
The main hypothesis on the cause of Alzheimer's involves
amyloid deposition, the
buildup of
plaques in the brain that impair neurological function; most biomedical efforts to tackle the disease have focused on this issue.
«This suggests that
amyloid buildup in the brain's blood vessels precedes
plaque formation in chimpanzees.»
The disease is largely attributed to an abnormal
buildup of proteins, which can form
amyloid beta
plaques and tangles in the brain that trigger inflammation and result in the loss of brain connections called synapses, the effect most strongly associated with cognitive decline.
The new therapy targets beta - secretase, an enzyme on neurons around which
plaques (
buildups of a protein called beta -
amyloid) cluster in the brain.
The DNA change may inhibit the
buildup of β
amyloid, the protein fragment that accumulates in the hallmark
plaques that form in the brains of Alzheimer's patients.
While the
buildup of sticky proteins called
amyloid plaques in the brain has been repeatedly linked to Alzheimer's disease, the role of blood in the formation of the condition has been less clear.
As I mentioned, a major trigger of memory loss is the
buildup of beta -
amyloid plaques in the brain.
Exciting new research shows that curcumin stops the process that causes the
buildup of beta -
amyloid plaques in the brain!
Studies indicate it protects and possibly reverses damage done by
amyloid - beta
plaque buildup in brain cells.
They also found that it plays a role in preventing the
buildup of beta -
amyloid plaque, which can be found in the brain of Alzheimer's patients.