Sentences with phrase «analysis of tumor tissue»

Importantly, without any prior knowledge from the analysis of tumor tissue, 76 % of «actionable» mutations (genetic changes that can be matched to an approved targeted therapy or one being tested in clinical trials) detected in tissue were also detected in blood.

Not exact matches

Analysis of blood and tissue samples from one patient revealed that plakoglobin was expressed in CTC clusters but not single CTCs and also was expressed in some portions of both the primary tumor and metastases.

«As there are no published guidelines for the use of ctDNA for EGFR mutation analysis in the absence of tumor tissue, these results may help address this current unmet need.»

Analysis of images showed that the contrast used by the research team bound almost exclusively to the fibrin - fibronectin complexes, producing a strong and prolonged image enhancement of micrometastases and tumors compared with normal tissue.

Using a very sensitive DNA analysis technique that can also be employed when only very small amounts of DNA from old tissue are available, the researchers could compare the two current cell lines with the tumor from which the cell line was established.

The biopsy of his primary tumor pointed to treatment with anti-HER2 therapy (Herceptin), but tissue from the metastatic biopsy, as well as cfDNA analysis, was negative for HER2 and positive for anti-epidermal growth factor receptor (EGFR) therapy (ABT - 806).

Patients with recurrent glioblastoma multiforme (GBM) treated with an experimental vaccine made from the patient's own resected tumor tissue showed an improved survival compared with historical patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro - Oncology and accompanied by an editorial highlighting the importance of the trial.

I am particularly interested in the neuronal tissue and the analysis of gene regulators implicated in both differentiation and brain tumor development.

We are using mouse models in conjunction with human tissue analysis to understand how this fibrosis arises and how it can be altered to allow access of chemotherapeutic agents to the tumor.

For AQUA analysis, 2 pairs of slides (containing two cores from different areas of each matching primary and metastatic tumor per patient) or test arrays of cores from FFPE placental tissue and MEL624 cells not overexpressing or overexpressing PD - L1 were concomitantly stained.

Tumor analyses commonly employ a correction with a matched normal (MN), a sample from healthy tissue of the same individual, in order to distinguish germline mutations from somatic mutations.

The analysis of 278 transposition - induced prostate, breast and skin tumors detected tissue - specific and shared data sets of known and candidate genes involved in cancer.

The diagnosis of the TVT was further supported by the identification and analysis of long interspersed nuclear elements (LINE) from paraffin - embedded tumor tissue.

This means there is no microscopic signs of tumor cells in the tissue submitted for analysis.

Your vet may stick a needle into the breast tissue and withdraw some of the tumor cells, or he may do a more invasive biopsy, involving actual surgery to remove the lump for pathological analysis.