Sentences with phrase «analysis suggests treatment»

«Our analysis suggests treatment of the retina with a large number of very small laser burns could prevent this «domino - like» progressive loss of small retinal blood vessels and prevent elevation of VEGF and the major complications of diabetic retinopathy,» Gast said.

Not exact matches

The primary outcome with the largest difference in this sensitivity analysis was preterm birth, where an analysis restricted to trials with lower risk of bias suggested a larger treatment effect: RR 0.64, (95 % CI 0.51 to 0.81) compared with RR 0.77, (95 % CI 0.62 to 0.94) in the overall analysis.

The analysis, published in August 2008 in The Lancet, suggests, «the infertility treatment per se for the outcomes we have studied does not seem to give any additional risk,» Romundstad says.

That's the controversial message from a recent analysis, which suggests that the main factor doctors use to assess suicide risk ends up diverting treatment away from people who may need it while over-treating those who may not.

Dr Jones, said: «This new meta - analysis shows that baclofen is no more effective than placebo on a range of key outcome measures, suggesting that the current increasing use of baclofen as a treatment for alcohol use disorders is premature.»

The work, which was propelled by technologies that enable the detailed analysis of even a handful of cells, opens a critical window on the biology of the disease and suggests a strategy for the development of more precise, powerful treatments.

A genetic analysis led by Dr. Erik Knudsen (left) and Dr. Agnieszka Witkiewicz suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for treatment.

Our analysis suggests putting treatment beds in place just one month earlier could have further reduced the size of the outbreak and potentially saved thousands of more lives.

The lifetime analysis suggested that first - line biologic treatment would result in 0.15 additional lifetime QALYs, but this gain would cost an incremental $ 77,290, leading to an incremental cost - effectiveness ratio of $ 521,520 per QALY per patient, a figure far above what is considered acceptable to the U.S. health care system.

A genetic analysis led by UT Southwestern Medical Center researchers suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for treatment.

The results suggest that genetic analysis might help dentists to personalize treatments for their patients, which could lead to improved outcomes.

«Exploratory analyses of several secondary outcomes indicated that the sedation protocol was associated with a difference in patients» sedation experience; patients in the intervention group were able to be safely managed in a more awake and calm state while intubated, receiving fewer days of opioid exposure and fewer sedative classes without an increase in inadequate pain or sedation management or clinically significant iatrogenic [consequence of treatment] withdrawal compared with patients receiving usual care, but they experienced more days with reported pain and agitation, suggesting a complex relationship among wakefulness, pain, and agitation,» the authors write.

«Analysis of metastatic prostate cancers suggests treatment options: Study maps out abnormal signaling pathways in prostate cancer cells and provides computational approaches to identify individualized targets for therapy.»

Bethesda, Md., Wed., May 1, 2013 - A comprehensive genomic analysis of nearly 400 endometrial tumors suggests that certain molecular characteristics - such as the frequency of mutations - could complement current pathology methods and help distinguish between principal types of endometrial tumors, as well as provide insights into potential treatment strategies.

Using gene expression profile (GEP) tests like Oncotype DX to inform treatment decision - making for breast cancer is likely to be less cost - effective in community oncology practice than previous estimates had suggested, according to an economic simulation analysis published in the Journal of Clinical Oncology.

Analysis carried out by Alzheimer's Research UK suggests that a treatment that could delay dementia by just five years would mean that 666,000 fewer people develop dementia by 2050 and save the economy billions every year.

High resolution kinetic analysis of IL - 6 and interferon responses revealed significant inhibition by IL - 13 treatment, suggesting an IL -13-mediated alteration of the resolution of the immune response.

Although triple negative cancer cells lack the three critical genetic markers that are currently used to guide breast cancer treatment, the scientists» analysis suggests a strong reliance on signaling through pathways similar to those that affect fetal breast stem cell growth.

Treatments vary widely for metastatic breast cancer patients, though an analysis suggests that costs per patient are relatively similar across a number of different tTreatments vary widely for metastatic breast cancer patients, though an analysis suggests that costs per patient are relatively similar across a number of different treatmentstreatments.

We strongly suggest to (1) repeat the semen analysis after 2 - 3 weeks to reduce the chance of outliers (in other words to «confirm low rapid linear progression») and to (2) discuss this matter with your personal doctor and / or fertility specialist to ensure an optimal course of treatment.

However, where the dog is limping as a result of the cracks, it suggests to me that a more in - depth analysis and treatment is necessary.

These frameworks both suggest a similar process that includes establishing the context, risk identification, risk analysis, risk evaluation and risk treatment.

Comments from the floor ranged from defensive (the APA staff essentially said, «If we want to be a player here with psychiatry we need to get these guidelines out now»; representatives from division 39, psychoanalysis, claimed unfair treatment of psychoanalysis and psychodynamic TX,) to accurate (the president of the Women's division strongly suggested that decontextualizing PTSD was dangerous to those who suffered from it,) to the idiotic (sorry about casting aspersions here — but I am always fascinated when psychologists in love with RCTs and meta - analyses as the only viable evidence base stand at the mic and spout effect sizes etc. — overlooking the important contributions from qualitative research, and misunderstanding how RCTs are based on drug trials that simply do not translate to humans.

Many trials used volunteers or people selected by referrers as willing to take part in parenting projects, thus excluding many disorganised, unmotivated, or disadvantaged families, who have the most antisocial children.2 A review of meta - analyses of published trials of psychological treatments for childhood disorders found that in university settings the effect size was large, from 0.71 to 0.84 SD.12 In contrast, a review of six studies of outcome in regular service clinics since 1950 showed no significant effects, 12 and a large trial offering unrestricted access to outpatient services found no improvement.13 Reasons suggested for the poor outcome in clinic cases include that they have more severe problems, come from more distressed families, and receive less empirically supported interventions from staff with heavier caseloads.

Nurse visited mothers showed higher levels of punishment and restriction, but the authors suggest that their analysis shows this level was associated with the lower instance of injuries and ingestions for the treatment group.

A study of individual cognitive therapy for bipolar disorder showed positive outcomes at 1 - year follow - up, but the benefits were reduced over time, suggesting the need for booster sessions to sustain the gains.19 As with many forms of therapy, CBT has been found to be more successful in reducing relapse in the depressive pole compared with the manic pole.30 A large randomised trial of CBT showed no difference between CBT and treatment as usual, when all participants were included in the analyses.31 However, results of a post-hoc analysis suggested that CBT was effective for participants who reported fewer than 12 prior episodes of illness and were not acutely unwell when therapy began; numbers of episodes of mania rather than depression seemed to predict treatment response.32 Such data can help guide the clinical application of CBT for bipolar patients.

Exploratory analyses suggested a possible mediating role of parenting in treatment outcomes for early adolescents, although this finding is preliminary and requires further exploration and replication.