Sentences with phrase «analyzed gene sequences»

The international team used a common computer system so that researchers from around the world could analyze the gene sequences based on their areas of expertise.

All the judges today agreed that our clients had standing to bring this case and that analyzing gene sequences for alterations is not patentable.

Not exact matches

Gene discovery was greatly facilitated by a new exome sequencing technology, which analyzes all protein - coding regions of the genome at once.

To derive an evolutionary tree of the TRIM5 gene, they analyzed and compared its complete protein - coding DNA sequences from 22 African primate species.

Brains of individuals who died with Huntington's, Parkinson's or no neurological condition were analyzed using sequencing technology that provides a data readout of the activity of all genes in the genome.

To solve the puzzle, he and Malaysian colleagues collected bits of the flower of Rafflesia keithii from Borneo and analyzed the DNA sequence of a gene called MatR.

The samples were analyzed by liquid chromatography - mass spectrometry (LC - MS) to characterize the metabolite composition («metabolomics»), and biocrust DNA was extracted for shotgun sequencing to measure single copy gene markers for the dominant microbe species («metagenomics»).

The latest gene - sequencing technologies developed by biotech companies 454 Life Sciences and Illumina can analyze several million DNA fragments at a time.

Gai and Falk used the high - performance computer cluster at Loyola's Center for Biomedical Informatics to analyze billions of DNA sequences to identify the gene mutation in the child and her parents.

Researchers analyzed the genetic sequencing data of 718 multiple myeloma patients and found that African - Americans had increased mutations in the genes BCL7A, BRWD3 and AUTS2, while white people had more mutations in the genes TP53 and IRF4.

The researchers analyzed and compared the evolutionary patterns of over 3500 toxin sequences from 85 gene families.

We analyzed 7.2 terabases of metagenomic data from 243 Tara Oceans samples from 68 locations in epipelagic and mesopelagic waters across the globe to generate an ocean microbial reference gene catalog with > 40 million nonredundant, mostly novel sequences from viruses, prokaryotes, and picoeukaryotes.

By analyzing more than a trillion sequencing letters, the team found over 100,000 gene switches.

When population geneticist Andrea Manica and graduate student Marcos Gallego Llorente at the University of Cambridge in the United Kingdom analyzed the sequence, they found that the Mota man had brown eyes and dark skin, as well as three gene variants associated with adaptation to high altitudes; some peaks in the highlands reach 4500 meters, as high as the Matterhorn.

After six to eight weeks, the microbial content of the mice's feces were analyzed by 16S ribosomal RNA gene sequencing, which showed that approximately 20 kinds of oral bacteria were present in these mice.

«We found global increases in many dozens of genes,» says Tavazoie, «so we analyzed their sequences and found that the majority of them had significantly increased numbers of these two specific codons.»

The researchers also analyzed parts of 19 genes, looking for changes in the DNA sequence from one species to the next.

The first study to sequence and analyze the entire genome of a HeLa cell line, along with access to its sequence data, has been published Aug. 7 in its final version, by G3: Genes Genomes Genetics, an open - access, scientific journal of the Genetics Society of America.

As a graduate student, she had begun analyzing and sequencing genes in 1995.

University of Nevada, Reno researchers, led by College of Science Assistant Professor David Alvarez - Ponce, have analyzed 322 animal genome sequences from the National Center for Biotechnology Information looking for animals that show the presence of active CMAH genes.

This represents a particular challenge to disease gene analysis: How do we analyze genes and establish genotype - phenotype relationships against a background of high natural genome sequence variability?

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

As Wroblewski, Parham, and co-authors explain in a PLOS Biology study published online today, they analyzed stool samples dating back 15 years and sequenced immune system genes from 125 chimpanzees.

Using whole exome sequencing (a next generation test to analyze the exons or coding regions of thousands of genes simultaneously) conducted at the Baylor College of Medicine Human Genome Sequencing Center, the researchers identified CLP1 mutations in two unrelated families with thesequencing (a next generation test to analyze the exons or coding regions of thousands of genes simultaneously) conducted at the Baylor College of Medicine Human Genome Sequencing Center, the researchers identified CLP1 mutations in two unrelated families with theSequencing Center, the researchers identified CLP1 mutations in two unrelated families with the disorder.

But after analyzing the Hofstenia transcriptome, the team determined that the three - banded panther worm and planarians are only very distantly related, a view that had been proposed based on analyses with sequences from a small number of genes.

The case is limited to patents that cover the sequence of a gene, rather than methods used to analyze it (see «A plethora of patents»).

The researchers analyzed DNA sequences known as transposons, or «jumping genes,» which can jump from one part of the genome to another, often duplicating themselves in the process.

To understand and analyze the regulation of gene expression patterns, quantitative RNA sequencing is used.

First, the researchers analyze sequence data from an individual's tumor and identify four to 10 genes altered in the cells.

One question in analyzing microbial communities by 16S rRNA gene pyrosequencing centers on whether the amplification and sequencing methods result in recovery of sequences in proportion to their representation in the original community [24].

Both groups are analyzing the sequence to identify genes that will reveal how the pathogen causes disease and interacts with the plant host.

His group analyzed the sequence and predicted functions for 3,475 genes.

Genomes that have been sequenced as part of a GWAS can be run through PrediXcan to generate a gene expression level profile, which is then analyzed to determine the association between gene expression levels and the disease states or the trait of interest being studied.

Zoghbi's lab meticulously analyzed each gene in this region, systematically eliminating genes based on sequence differences between healthy controls and Rett syndrome patients.

The MyAML and MyHEME cancer panels are designed to analyze and interpret sequence information in genes known or suspected to be involved in AML and other hematologic diseases, respectively.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

The researchers then analyzed another 147 colorectal cancer cell lines in the same way for kinase - domain mutations in these genes, and then sequenced the entire coding region of all kinases that were mutated, in all discovering 46 new mutations.

We can leverage the lowering cost of gene sequencing to interrogate cells at a deeper level, and use computational tools to analyze the resulting data.

The study was among the first to use large - scale DNA sequencing to systematically analyze all 86 members of the PTK gene family in melanoma samples.