This not only ensures that sister chromatids remain cohesed until the metaphase - to -
anaphase transition, but also provides us with the stereotypical image of an X-shaped chromosome.
DNA damage leads to a Cyclin A — dependent delay in metaphase -
anaphase transition in the < i > Drosophila gastrula.
However, mitotic cells showed a rapid elevation of [Ca2 +] i from basal levels of 130 nM to 500 to 800 nM at the metaphase -
anaphase transition.