Scientists hope the hundreds
of thousands
of images they produce will help them zero in on
brain wiring and
anatomical differences in children that develop disorders such as autism.
The group employed various viral tracing methods — infecting receptor - expressing neurons with a virus strain and watching them spread as they label infected cells with a fluorescent protein — to visualize the neural circuit downstream
of the ESP1 receptor, as well as providing an
image of nerve fibers belonging to specific neurons in the
brain and synapses relaying impulses from neuron to neuron, to map the
anatomical foundation that conveys ESP1 signals in the
brain.
The first accurate pictures
of the human
brain date back to the 1660s, when English physician Thomas Willis published
anatomical images created by his assistant, medical illustrator Christopher Wren.